Share This Article:

Effects of Yogurt Containing Lactobacillus gasseri OLL2716 on Autonomic Nerve Activities and Physiological Functions

Abstract Full-Text HTML XML Download Download as PDF (Size:319KB) PP. 397-405
DOI: 10.4236/health.2015.73045    3,094 Downloads   3,699 Views   Citations

ABSTRACT

The purpose of this study was to investigate the effects of yogurt containing Lactobacillus gasseri OLL2716 (LG21) on autonomic nerve activities, peripheral blood flow, skin condition (skin pig-mentations and moisture), saliva s-IgA and examination of quality of life (QOL). 20 healthy female volunteers (yogurt containing LG21 group: 10 people, yogurt containing Bifidobacterium (Bif) group: 10 people) were examined. The subjects ingested 100 g of yogurt twice daily for 4 weeks. Analysis was before and after 4 weeks dosage. By the effects for the autonomic nervous activity, parasympathetic increase was observed in the LG21 yogurt group, but was not significant increase. The LG21 yogurt was significantly increased on the peripheral blood flow. The LG21 yogurt was significantly increased on saliva s-IgA. The LG21 yogurt and Bif yogurt were significantly decrease on skin pigmentation. Also, LG21 yogurt was significantly increased on skin moisture. As a result of QOL questionnaire, incomplete evacuation, lower abdominal fullness, cold extremities and pimply or rough skin improved in LG21 yogurt and Bif yogurt after the administration period. These results suggest that the improvement effects of LG21 yogurt may be related to the activity of the parasympathetic nervous system.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Otomi, K. , Ymaguchi, T. , Watanabe, S. , Kobayashi, A. , Kobayashi, H. and Hashiguchi, N. (2015) Effects of Yogurt Containing Lactobacillus gasseri OLL2716 on Autonomic Nerve Activities and Physiological Functions. Health, 7, 397-405. doi: 10.4236/health.2015.73045.

References

[1] Fuller, R. (1989) Probiotics in Man and Animals. Journal of Applied Bacteriology, 66, 365-378.
http://dx.doi.org/10.1111/j.1365-2672.1989.tb05105.x
[2] Probiotics in Food. Health and Nutritional Properties and Guidelines for Evaluation.
ftp.fao.org/docrep/fao/009/a0512e/a0512e00.pdf
[3] Sakamoto, I., Igarashi, M., Kimura, K., Takagi, A., Miwa, T. and Koga, Y. (2001) Suppressive Effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori Infection in Humans. Journal of Antimicrobial Chemotherapy, 47, 709-710.
http://dx.doi.org/10.1093/jac/47.5.709
[4] Fujimura, S., Kato, S., Oda, M., Miyahara, M., Ito, Y., Kimura, K., Kawamura, T., Ohnuma, M., Tateno, H. and Watanabe, A. (2006) Detection of Lactobacillus gasseri OLL2716 Strain Administered with Yogurt Drink in Gastric Mucus Layer in Humans. Letters in Applied Microbiology, 43, 578-581.
http://dx.doi.org/10.1111/j.1472-765X.2006.02017.x
[5] Uchida, M., Shimizu, K. and Kurakazu, K. (2010) Yogurt Containing Lactobacillus gasseri OLL 2716 (LG21 Yogurt) Accelerated the Healing of Acetic Acid-Induced Gastric Ulcer in Rats. Bioscience, Biotechnology, and Biochemistry, 74, 1891-1894.
http://dx.doi.org/10.1271/bbb.100287
[6] Deguchi, R., Nakaminami, H., Rimbara, E., Noguchi, N., Sasatsu, M., Suzuki, T., Matsushima, M., Koike, J., Igarashi, M., Ozawa, H., Fukuda, R. and Takagi, A. (2011) Effect of Pretreatment with Lactobacillus gasseri OLL2716 on First-Line Helicobacter pylori Eradication Therapy. Journal of Gastroenterology and Hepatology, 27, 888-892.
http://dx.doi.org/10.1111/j.1440-1746.2011.06985.x
[7] Itoh, H., Uchida, M., Sashihara, T., Ji, Z.S., Li, J., Tang, Q., Ni, S., Song, L. and Kaminogawa, S. (2011) Lactobacillus gasseri OLL2809 Is Effective Especially on the Menstrual Pain and Dysmenorrhea in Endometriosis Patients: Randomized, Double-Blind, Placebo-Controlled Study. Cytotechnology, 63, 153-161.
http://dx.doi.org/10.1007/s10616-010-9326-5
[8] Forrester, K.R., Stewart, C., Tulip, J., Leonard, C. and Bray, R.C. (2002) Comparison of Laser Speckle and Laser Doppler Perfusion Imaging: Measurement in Human Skin and Rabbit Articular Tissue. Medical & Biological Engineering & Computing, 40, 687-697.
http://dx.doi.org/10.1007/BF02345307
[9] Merla, A., Di Donato, L., Romani, G.L., Proietti, M. and Salsano, F. (2008) Comparison of Thermal Infrared and Laser Doppler Imaging in the Assessment of Cutaneous Tissue Perfusion in Scleroderma Patients and Healthy Controls. International Journal of Immunopathology and Pharmacology, 21, 679-686.
[10] Tanida, M., Yamano, T., Maeda, K., Okumura, N., Fukushima, Y. and Nagai, K. (2005) Effects of Intraduodenal Injection of Lactobacillus johnsonii La1 on Renal Sympathetic Nerve Activity and Blood Pressure in Urethane-Anesthetized Rats. Neuroscience Letters, 389, 109-114.
http://dx.doi.org/10.1016/j.neulet.2005.07.036
[11] Yamano, T., Tanida, M., Niijima, A., Maeda, K., Okumura, N., Fukushima, Y. and Nagai, K. (2006) Effects of the Probiotic Strain Lactobacillus johnsonii Strain La1 on Autonomic Nerves and Blood Glucose in Rats. Life Sciences, 79, 1963-1967.
http://dx.doi.org/10.1016/j.lfs.2006.06.038
[12] Nasu, Y., Iwashita, M., Saito, M., Fushiya, S. and Nakahata, N. (2009) Inhibitory Effects of Atractylodis Lanceae Rhizoma and Poria on Collagen- or Thromboxane A2-Induced Aggregation in Rabbit Platelets. Biological and Pharmaceutical Bulletin, 32, 856-860.
http://dx.doi.org/10.1248/bpb.32.856
[13] Perdigón, G., de Moreno de LeBlanc, A., Valdez, J. and Rachid, M. (2002) Role of Yoghurt in the Prevention of Colon Cancer. European Journal of Clinical Nutrition, 56, S65-S68.
http://dx.doi.org/10.1038/sj.ejcn.1601490
[14] Kawamoto, S., Tran, T.H., Maruya, M., Suzuki, K., Doi, Y., Tsutsui, Y., Kato, L.M. and Fagarasan, S. (2012) The Inhibitory Receptor PD-1 Regulates IgA Selection and Bacterial Composition in the Gut. Science, 336, 485-489.
http://dx.doi.org/10.1126/science.1217718
[15] Suzuki, K., Meek, B., Doi, Y., Muramatsu, M., Chiba, T., Honjo, T. and Fagarasan, S. (2004) Aberrant Expansion of Segmented Filamentous Bacteria in IgA-Deficient Gut. Proceedings of the National Academy of Sciences of the United States of America, 101, 1981-1986.
http://dx.doi.org/10.1073/pnas.0307317101
[16] Moreau, M.C., Hudault, S. and Bridonneau, C. (1990) Systemic Antibody Response to Ovalbumin in Gnotobiotic C3H/HeJ Mice with Bifidobacterium bifidum or Escherichiacoli. Microecology and Therapy, 20, 309-312.
[17] Isawa, K., Noma, T., Yamamoto, M., Kimura, K., Ito, H., Taketomo, N., Numano, K. and Kawashima, M. (2008) Verifying the Ability of Yogurt Prepared with LB81 Lactic Acid Bacteria to Improve Skin Function. Journal of Intestinal Microbiology, 22, 1-5.
[18] Sashihara, T. (2013) Effects of Lactic Acid Bacteria on Immune Regulatory Activities. Journal of Intestinal Microbiology, 27, 197-202.

  
comments powered by Disqus

Copyright © 2018 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.