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Spatial Analysis of Leptospira in Rats, Water and Soil in Bantul District Yogyakarta Indonesia

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DOI: 10.4236/ojepi.2015.51004    3,460 Downloads   4,339 Views   Citations

ABSTRACT

Leptospirosis is a potential threat to public health. An increasing number of people infected with Leptospira were reported in Bantul District, Yogyakarta special region with a case fatality rate (CFR) of 7.8%. Infected areas in the district have increased from 2 to 15 sub districts. Leptospirosis is caused by Leptospira bacteria and spread by direct contact with infected rodents and indirect contact through contaminated water or soil. Leptospira in rats, water and soil were detected using real-time quantitative polymerase chain reaction (qPCR). The sites of sampled materials were geocoded using Global Positioning System (GPS). Spatial analysis was used to predict the spread of Spira. This study aims to perform the mapping, clustering, and predicting the spread of Leptospira in Bantul Yogyakarta Indonesia. Data were collected from three sub-districts: Sedayu, Sewon and Bantul. The result showed that 38.04% from 368 samples were Spira positive. There were four significant clusters of infection spread source. Spira is predicted to spread in, and out from, Bantul District.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Sumanta, H. , Wibawa, T. , Hadisusanto, S. , Nuryati, A. and Kusnanto, H. (2015) Spatial Analysis of Leptospira in Rats, Water and Soil in Bantul District Yogyakarta Indonesia. Open Journal of Epidemiology, 5, 22-31. doi: 10.4236/ojepi.2015.51004.

References

[1] Bharti, A.R., Nally, J.E., Ricaldi, J.N., Matthias, M.A., Diaz, M.M., Lovett, M.A., Levett, P.N., Gilman, R.H., Willig, M.R., Gotuzzo, E. and Vinetz, J.M. (2003) Leptospirosis: A Zoonotic Disease of Global Importance. The Lancet Infectious Diseases, 3, 757-771.
http://dx.doi.org/10.1016/S1473-3099(03)00830-2
[2] McBride, A.J.A., Santos, B.L., Queiroz, A., Santos, A.C., Hartskeerl, R.A., Reis, M.G., Ko, A.I. and Santos, C. (2007) Evaluation of Four Whole-Cell Leptospira-Based Serological Tests for Diagnosis of Urban Leptospirosis. Clinical and Vaccine Immunology, 14, 1245-1248.
http://dx.doi.org/10.1128/CVI.00217-07
[3] WHO (2007) Leptospirosis. Laboratory Manual.
[4] Levett, P.N. (2001) Leptospirosis. American Society for Microbiology, 14, 296-326.
[5] McBride, A., Athanazio, D., Reis, M. and Ko, A. (2005) Leptospirosis. Current Opinion in Infectious Diseases, 18, 376-386.
http://dx.doi.org/10.1097/01.qco.0000178824.05715.2c
[6] Matthias, M.A., Ricaldi, J.N., Cespedes, M., Diaz, M.M., Galloway, R.L., Saito, M., Steigerwalt, A.G., Patra, K.P., Ore, C.V., Gotuzzo, E., Robert, H., Levett, P.N. and Vinetz, J.M. (2008) Human Leptospirosis Caused by a New, Antigenically Unique Leptospira Associated with a Rattus Species Reservoir in the Peruvian Amazon. PLOS Neglected Tropical Diseases, 2, 1-12.
http://dx.doi.org/10.1371/journal.pntd.0000213
[7] Michna, S.W. (1970) Leptospirosis. Veterinary Record, 86, 484-496.
http://dx.doi.org/10.1136/vr.86.17.484
[8] Faine, S., Adler, B., Bolin, C. and Perolat, P. (1999) Leptospira and Leptospirosis. 2nd Edition, Medisci Press, Melbourne.
[9] Ido, Y., Hoki, R., Ito, H. and Wani, H. (1979) The Rat as a Carrier of Spiroci-I~Ta Ictero-Hiemorrhagi~E, the Causative Agent of Weil’s Disease (Spiroch./Etosis Icterohiemorrhagica). Tokyo Iji-Shuho.
[10] Chappel, R.J., Prime, R.W., Millar, B.D., Jones, R.T., Cutler, R.S. and Adler, B. (1998) Prevalence and Geographic Origin of Pigs with Serological Evidence of Infection with Leptospira Interrogans Serovar Pomona Slaughtered in Abattoirs in Victoria, Australia. Veterinary Microbiology, 62, 235-242.
http://dx.doi.org/10.1016/S0378-1135(98)00203-X
[11] Geisen, V., Stengel, C., Brem, S., Muller, W., Greene, C. and Hartmann, K. (2007) Canine Leptospirosis Infections? Clinical Signs and Outcome with Different Suspected Leptospira Serogroups (42 Cases). Journal of Small Animal Practice, 48, 324-328.
http://dx.doi.org/10.1111/j.1748-5827.2007.00324.x
[12] Zakeri, S., Sepahian, N., Afsharpad, M., Esfandiari, B., Ziapour, P. and Djadid, N.D. (2010) Molecular Epidemiology of Leptospirosis in Northern Iran by Nested Polymerase Chain Reaction/Restriction Fragment Length Polymorphism and Sequencing Methods. American Journal of Tropical Medicine and Hygiene, 82, 899-903.
http://dx.doi.org/10.4269/ajtmh.2010.09-0721
[13] Faine, S., Adler, B., Bolin, C. and Perolat, P. (1999) Leptospira and Leptospirosis. 2nd Edition, Medisci Press, Melbourne.
[14] Widarso, H., Wilfried, P. and Gasem, M. (2003) Pedoman Diagnosa dan Penatalaksanaan Kasus Penanggulangan Leptospirosis di Indonesia. Jakarta: Direktorat Jenderal PPM-PL, Subdit Zoonosis, Departemen Kesehatan.
[15] Rejeki, D.S.S. (2005) Faktor Risiko Lingkungan yang Berpengaruh Terhadap Kejadian Leptospirosis Berat. Universitas Diponegoro, Semarang.
[16] Gambiro and Wahyuni (2005) Laporan survey reservoir leptospirosis di Kabupaten Demak dan Kota Semarang Provinsi Jawa Tengah. Provinsi Jawa Tengah.
[17] Dinas Kesehatan Kabupaten Bantul (2013) Laporan Angka Kejadian Leptospirosis Tahun 2012.
[18] Syamsumin, D., Nurbeti, K., Syariffudin, V., Faisal, E., Rahayujati, B.T. and Santosa, T.B.H. (2010) Investigasi Kejadian Luar Biasa (KLB) Leptospirosis di Kabupaten Bantul, Provinsi Daerah Istimewa Yogyakarta. FETP-FK UGM.
[19] Melani, S. (2010) Analisis Spasiotemporal Kasus Leptospirosis di Kota Semarang Tahun 2009. Fakultas Kedokteran, Universitas Diponegoro, Semarang.
[20] Asyhar, T. (2008) Analisis Spasial Faktor Risiko Lingkungan pada Kejadian Leptospirosis di Kota Semarang.
[21] Sunaryo (2009) Kajian Berbasis Citra Penginderaan Jauh dan Sistem Informasi Geografis untuk Pemetaan dan Analisis Faktor Risiko Leptospirosis (Studi Kasus di Kota Semarang, Provinsi Jawa Tengah). Fakultas Geografi Universitas Gadjah Mada, Yogyakarta.
[22] Fuadi, A. (2012) Hubungan Ternak Sapi Sebagai Reservoir Leptospira dengan Kejadian Leptospirosi pada Peternak di Kabupaten Bantul.
[23] Dohoo, L., Martin, W. and Stryshn, H. (2003) Veterinary Epidemiologic Research. National Library of Canada, Canada, 47-49.
[24] Rochman, D., Sukarna and Suwalan (1999) Pola perkembangbiakan tikus sawah Rattus argentiventer pada berbagai daerah berpola tanam padi-padi di subang. Penelitian Pertanian, 2, 77-80.
[25] Ristiyanto (2007) Sosialisasi Pengendalian tikus untuk pencegahan leptospirosis. Balai Besar Penelitian dan Pengembangan Vektor dan Reservoir Penyakit, Badan Penelitian dan Pengembangan Kesehatan, Departemen Kesehatan RI, Salatiga.
[26] Smythe, L.D., Smith, I.L., Smith, G.A., Dohnt, M.F., Symonds, M.L., Barnett, L.J. and Mckay, D.B. (2002) A Quantitative PCR (TaqMan) Assay for Pathogenic Leptospira spp. BMC Infectious Diseases, 2, 1-7
http://dx.doi.org/10.1186/1471-2334-2-13
[27] McBride, A.J.A., Santos, B.L., Queiroz, A., Santos, A.C., Hartskeerl, R.A., Reis, M.G. and Ko, A.I. (2007) Evaluation of Four Whole-Cell Leptospira-Based Serological Tests for Diagnosis of Urban Leptospirosis. Clinical and Vaccine Immunology, 14, 1245-1248.
http://dx.doi.org/10.1128/CVI.00217-07
[28] Anies, Hadisaputro, S., Sakundarno, M. and Suhartono (2009) Lingkungan dan Perilaku pada Kejadian Leptospirosis. Media Medika Indonesiana, 43, 306-311.
[29] Lestariningsih (2002) Kelainan Ginjal pada Leptospirosis. In: Budi, R., H., G. and Muchlis, A.U.S., Eds., Kumpulan Makalah Simposium Leptospirosis, Universitas Diponegoro, Semarang, 47-53.
[30] Murtiningsih, B. (2003) Faktor resiko kejadian leptospirosis di provinsi daerah istimewa yogyakarta dan sekitarnya.
[31] Agustini, M. (2011) Environmental of Leptospirosis Endemic Area at Sumbersari Village, Moyudan Subdistrict, Sleman Regency Yogyakarta Special Region Province. Gadjah Mada University, Yogyakarta.
[32] Widarso, H., Husen, G., Wilfried, P., Tato, S., Endang, B., Septiawatichita and Pranti, S.M. (2005) Pedoman penanggulangan Leptospirosis Di Indonesia. Sub Ditrektorat Zoonosis. Direktorat Jenderal Pemberantasan Penyakit Menular dan Penyehatan lingkungan Dep Kes RI.
[33] Simanjuntak, G., Koesharjono, C. and Hardjoutomo, S. (1986) Leptospirosis di daerah transmigrasi Kuala Cinaku propinsi Riau tahun 1981. Penyakit Hewan, 18, 6-13.
[34] Priyanto, A., Hadisaputro, S., Santoso, L., Gasem, H. and Adi, S. (2008) Faktor-Faktor Risiko Yang Berpengaruh Terhadap Kejadian Leptospirosis (Studi Kasus di Kabupaten Demak). Universitas Diponegoro, Semarang.
[35] Haake, D.A., Dundoo, M., Cader, R., Kubak, B.M., Hartskeerl, R.A., Sejvar, J.J. and Ashford, D.A. (2002) Leptospirosis, Water Sports, and Chemoprophylaxis. Clinical Infectious Diseases, 34, 40-43.
[36] Ikawati, B. (2010) Analisis Karakteristik Lingkungan Pada Kejadian Leptospirosis di Kabupaten Demak Jawa Tengah Tahun 2009. Media Kesehatan Masyarakat Indonesia, 9, 33-40.
[37] Faine, S. (1982) Guidelines for the Control of Leptospirosis. Department of Microbiology Monash University, Melbourne, 1-200.
[38] Barcellos, C. and Sabroza, P.C. (2001) The Place behind the Case: Leptospirosis Risks and Associated Environmental Conditions in a Flood-Related Outbreak in Rio de Janeiro (O lugar do caso: Leptospirose e riscos associados a condiates ambientais durante o surto de 1996 na Zona Oeste do Rio de Janeiro). Cadernos de Saúde Pública, 17, 59-67.
[39] Urmimala, S. (2002) Population Based Case Control Investigation of Risk Factor for Leptospirosis during an Urban Epidemic. American Journal Tropical Medicine and Hygiene, Salvador, 605-610.
[40] Priyambodo, S. (1995) Pengendalian Hama Tikus Terpadu. PT Penebar Swadaya, Jakarta.
[41] Nurbeti, M. (2012) Kasus-Kasus Leptospirosis Di Perbatasan Kabupaten Bantul, Sleman, Dan Kulon Progo: Analisis Spasial. Universitas Gadjah Mada, Yogyakarta.
[42] Dinas Kesehatan Kabupaten Bantul (2012) Laporan Angka Kejadian Leptospira Tahun 2011. Bantul.

  
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