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Introduction of Inactivated Polio Vaccine and Specific Determinants of Vaccine Hesitancy

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DOI: 10.4236/wjv.2015.51002    7,000 Downloads   7,773 Views   Citations

ABSTRACT

Background: Introduction of inactivated polio vaccine is imminent and may encounter the challenges that face new vaccines especially vaccine hesitancy. The study evaluated factors that may contribute to hesitancy towards IPV. Methods: Questionnaire adapted from the model developed by the Strategic Advisory Group of Experts Working Group (SAGE WG) was used to assess the factors among 408 parents. The evaluation was under the 3 Cs: Confidence, Complacency and Convenience. Questions were scored on Likert 4-unit-scale system. The data were analyzed using SPSS and, multivariate analysis was used to further test individual significant variables. Results: Overall, Complacency (2.29) and Convenience (2.11) domains were more pro-vaccine hesitant, than Confidence (1.83) domain. However, none was significantly associated with likelihood of a parent’s hesitancy towards IPV vaccination. But certain individual questions: competence of vaccinators (p = 0.04), confidence that their child will not to be infected with poliomyelitis even when not vaccinated (p = 0.03) and, willingness to vaccinate with IPV when OPV is still in use (p = 0.01) were significantly associated with vaccine hesitancy. Conclusions: None of the factors can individually influence acceptance of IPV. However, competence of vaccinators, parental belief and availability of close alternative influenced parental decision to vaccinate.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Ughasoro, M. , Tagbo, B. and Esangbedo, D. (2015) Introduction of Inactivated Polio Vaccine and Specific Determinants of Vaccine Hesitancy. World Journal of Vaccines, 5, 8-18. doi: 10.4236/wjv.2015.51002.

References

[1] Hajjeh, R.A., Privor-Dumm, L., Edmond, K., O’Loughlin, R.O., Shetty, S., Griffiths, U.K., Bear, A.P., Cohen, A.L., Chandran, A., Schuchat, A., Mulholland, E.K. and Santosham, M. (2010) Supporting New Vaccine Introduction Decisions: Lessons Learned from the Hib Initiative Experience. Vaccine, 28, 7123-7129.
http://dx.doi.org/10.1016/j.vaccine.2010.07.028
[2] Haemophilus Influenza Type b Vaccine Support. Gavi the Vaccine Alliance. www.gavi.org/support/nvs/hib/
[3] Abdulkarim, A.A., Ibrahim, R.M., Fawi, A.O., Adebayo, O.A. and Johnson, A.W.B.R. (2011) Vacines and Immunization: The Past, Present and Future in Nigeria. Nigerian Journal of Paediatrics, 38, 186-194.
http://dx.doi.org/10.4314/njp.v38i4.72382
[4] PAN Advisory Committee on Immunization (2012) Paediatric Association of Nigria (PAN) Recommendation Routine Immunization Schedule for Nigeria Children. Nigerian Journal of Paediatrics, 39, 152-158.
[5] Ehrenfeld, E., Glass, R.I., Agol, V.I., Chumakov, K., Dowdle, W., John, T.J., Katz, S.L., Miller, M., Breman, J.G., Modlin, J. and Wright, P. (2008) Immunization against Poliomyelitis: Moving Forward. The Lancet, 371, 1385-1387.
http://dx.doi.org/10.1016/S0140-6736(08)60597-8
[6] Report of the SAGE Working Group on Vaccine Hesitancy. www.who.int/immunization/sage/meetings/2014/october/1_report_WORKING_GROUP_vaccine_hesitancy_final.pdf
[7] Larson, H.J., Jarrett, C., Eckersberger, E., Smith, D. and Paterson, P. (2014) Understanding Vaccine Hesitancy around Vaccines and Vaccination from a Global Perspective: A Systematic Review of Published Literature, 2007-2012. Vaccine, 32, 2150-2159.
[8] Ube, P.A., Richardson, J. and Menzel, P. (2000) Societal Value, the Person Trade-Off, and the Dilemma of Whose Values to Measure for Cost-Effectiveness Analysis. Health Econ, 9, 127-126.
http://dx.doi.org/10.1002/(SICI)1099-1050(200003)9:2<127::AID-HEC500>3.0.CO;2-Y
[9] O’Brien, B. and Gafni, A. (1996) When Do the “Dollars” Make Sense? Toward a Conceptual Framework for Contigent Valuation Studies in Health Care. Medical Decision Making, 16, 288-299.
http://dx.doi.org/10.1177/0272989X9601600314
[10] Hinman, A.R., Foege, W.H., de Quadros, C.A., Patriarca, P.A., Orenstein, W.A. and Brink, E.W. (1987) The Case for Global Eradication of Poliomyelitis. Bulletin of the World Health Organization, 65, 835-840.
[11] Hull, H.F. and Lee, J.W. (1996) Sabin, Salk or Sequential? Lancet, 347, 630.
http://dx.doi.org/10.1016/S0140-6736(96)91194-0
[12] Gust, D.A., Strine, T.W., Maurice, E., Smith, P., Yusuf, H., Wilkinson, M., et al. (2004) Underimmunization among Children: Effect of Vaccine Safety Concerns on Immunization Status. Pediatrics, 114, e16-e22.
http://dx.doi.org/10.1542/peds.114.1.e16
[13] Shui, I.M., Weintraub, E.S. and Gust, D.A. (2006) Parents Concerned about Vaccine Safety: Differences in Race/Ethnicity and Attitudes. American Journal of Preventive Medicine, 31, 244-251.
http://dx.doi.org/10.1016/j.amepre.2006.04.006
[14] Gust, D., Brown, C., Sheedy, K., Hibbs, B., Weaver, D. and Nowak, G. (2005) Immunization Attitudes and Beliefs among Parents: Beyond a Dichotomous Perspective. American Journal of Health Behavior, 29, 81-92.
http://dx.doi.org/10.5993/AJHB.29.1.7
[15] Gust, D.A., Darling, N., Kennedy, A. and Schwartz, B. (2008) Parents with Doubts about Vaccines: Which Vaccines and Reasons Why. Pediatrics, 122, 718-725.
http://dx.doi.org/10.1542/peds.2007-0538
[16] Patel, M.M., Janssen, A.P., Tardif, R., Herring, M. and Parashar, U.D. (2007) A Qualitative Assessment of Factors Influencing Acceptance of New Rotavirus Vaccine among Health Care Provider and Consumers. BMC Pediatrics, 7, 32.
http://dx.doi.org/10.1186/1471-2431-7-32
[17] Williams, S.E., Rothman, R.L., Offit, P.A., Schaffner, W., Sullivan, M. and Edwards, K.M. (2013) A Randomized Trial to Increase Acceptance of Childhood Vaccines by Vaccine-Hesitant Parents: A Pilot Study. Academic Pediatrics, 13, 475-480.
http://dx.doi.org/10.1016/j.acap.2013.03.011
[18] Oyedeji, G.A. (1985) Socioeconomic and Cultural Background of Hospitalized Children in Ilesha. Nigerian Journal of Paediatrics, 12, 111-117.
[19] Tagbo, B.N., Ughasoro, M.D. and Esangbedo, D.O. (2014) Parental Acceptance of Inactivated Polio Vaccine in Southeast Nigeria: A Qualitative Cross-Sectional Interventional Study. Vaccine, 32, 6157-6162.
http://dx.doi.org/10.1016/j.vaccine.2014.08.053
[20] Salsberry, P., Nickel, J. and Mitch, R. (1993) Why Aren’t Preschoolers Immunized? A Comparison of Parents’ and Providers’ Perceptions of the Barriers to Immunizations. Journal of Community Health Nursing, 10, 213-224.
http://dx.doi.org/10.1207/s15327655jchn1004_2
[21] Nichter, M. (1990) Vaccination in South Asia: False Expectations and Commanding Metaphors. In: Coreil, J., Ed., Anthropology and Primary Health Care, Westview Press, Oxford, 196-221.
[22] Expanded Programme on Immunization (1998) The Social Science and Immunization Research Project. Weekly Epidemiological Record, 73, 285-288.
[23] Wright Clayton, E., Hickson, G.B. and Miler, C.S. (1994) Parents’ Responses to Vaccine Information Pamphlets. Pediatrics, 93, 369-372.
[24] St-Armour, M., Guay, M., Parron, L., Clément, P., Baron, G., Petit, G. and Lemaire, J. (2006) Are Vaccination Information Leaflets Useful for Vaccinators and Parents? Vaccine, 24, 2491-2496.
[25] Salmon, D.A., Sotir, M.J., Pan, W.K., Berg, J.L., Omer, S.B., Stokley, S., et al. (2009) Parental Vaccine Refusal in Wisconsin: A Case-Control Study. WMJ, 108, 17-23.
[26] Lagarde, F. (2005) Summary of Public Opinion on Immunization in Canada. Public Health Agency of Canada, Ottawa, 19.

  
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