Erratum to “Addition of Metanx in Pregabalin Partial Responders for Painful Diabetic Neuropathy”

Allen Mark Jacobs, Dunlei Cheng

Saint Louis University School of Medicine, Saint Louis, USA.
University of Texas School of Public Health, Dallas, USA.

DOI: 10.4236/jdm.2014.43035                

Abstract

Objective: To study the effect of addition of Metanx on burning parasthesias in patients with symptomatic diabetic neuropathy who had obtained only partial symptom resolution with pregabalin. Research design and methods: This was an open-label pilot study. There were 16 patients (7 males, 9 females) in the study group and 8 patients (3 males, 5 females) in the control group. A patient numeric rating scale (0 - 10) of neuropathy associated pain was obtained at baseline and at 20 weeks. The control group continued on a fixed dosage of pregabalin without additional medication, while the study group was supplemented with Metanx (a proprietary blend of bioactive B-vitamins), in addition to being continued on a fixed dosage of pregabalin. Results: After 20 weeks, significantly more patients in the study group experienced pain relief compared to the control group (87.5% vs. 12.5%, respectively, p =0.005). The average pain score reduction after 20 weeks in the study group was 3 compared to0.25 inthe control group (p < 0.001). Conclusion: Our study suggested that addition of Metanx may be used for the relief of pain in patients that have obtained only partial resolution of symptomatology from pregabalin.

Keywords

L-Methylfolate; Methylcobalamin; Metanx; Diabetic Neuropathy

http://dx.doi.org/10.4236/jdm.2013.33020) was published in August, 2013. The author wishes to correct the following error:

Instead of Abstract Results: After 20 weeks, patients in the study group experienced greater pain relief compared to the control group, (87.5% vs. 25% respectively, p = 0.005).

Should read Abstract Results: After 20 weeks, significantly more patients in the study group experienced pain relief compared to the control group (87.5% vs. 12.5%, respectively, p = 0.005).

Conflicts of Interest

The authors declare no conflicts of interest.

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