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Synthesis and X-Ray Structure of New Anticancer Nucleosides Based on 1-((2-Hydroxyethoxy)methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide

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DOI: 10.4236/jcpt.2014.43017    4,184 Downloads   4,923 Views  

ABSTRACT

A pair of new anticancer nucleosides based on 1,2,4-triazole nucleosides and 1-((2-hydroxyethoxy) methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide have been synthesized, and have given the corresponding products in excellent yields. Its structures and conformations were confirmed by single crystal X-ray diffraction.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Lei, Y. , Zhang, D. , Liu, Y. , Tian, G. and Ge, H. (2014) Synthesis and X-Ray Structure of New Anticancer Nucleosides Based on 1-((2-Hydroxyethoxy)methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide. Journal of Crystallization Process and Technology, 4, 135-139. doi: 10.4236/jcpt.2014.43017.

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