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Estimation of Standard Splenic Volume in Saudi Arabian Adult Population: Using 3D Reconstruction of Abdominal CT Scan Images

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DOI: 10.4236/ojim.2014.41002    3,409 Downloads   5,016 Views   Citations

ABSTRACT

Purpose: Spleen is enlarged in a variety of clinical conditions including infectious, infiltrative, immunologic and malignant states. Evaluation of splenic size is important in every physical examination of the abdomen by a physician. Determination of its size by palpation can be extremely inaccurate because spleen is never palpable till it is enlarged 2 to 3 times its own size. The accurate diagnosis of splenic enlargement is a matter of considerable importance as it is a useful guide for arriving at a diagnosis of the disease. It is therefore of utmost importance to resort to a mechanism that will give us an accurate estimation of the size of spleen. Aim of this work was to determine the normal range of spleen dimensions in average adult Saudi Arabian population and compare it with the published data. Methods: CT scans of 34 adult patients (male and female) aged between 20 - 70 years, having no splenic disorders, were collected from department of radio-diagnosis King Khalid Hospital Al-Kharj, KSA. Splenic volume was measured by two methods—by volumetric software and the prolate ellipsoid formula. Results: The average splenic volume of all subjects was 161.42 ± 54.91 cm3 with a range of 106 - 319 cm3. The average splenic volume of males was 196.95 ± 48.70 cm3 and that of female was 196.95 ± 26.97 cm3. Conclusions: These results provide normative data for evaluating patients with splenic enlargement.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Aslam Siddiqui, M. , Hassan A. Ali, A. , Abdelmohsen Bedewi, M. and O. Serhan, O. (2014) Estimation of Standard Splenic Volume in Saudi Arabian Adult Population: Using 3D Reconstruction of Abdominal CT Scan Images. Open Journal of Internal Medicine, 4, 7-12. doi: 10.4236/ojim.2014.41002.

References

[1] Douglas, G., Nicol, F. and Robertson, C. (2009) Macleod’s Clinical Examination. 12th Edition, Churchill Livingstone, Elsevier, Philadelphia.
[2] Sinnatamby, C.S. (2006) Last’s Anatomy: Regional and Applied. 11th Edition, Churchill Livingstone, Elsevier, Saunders, New York.
[3] Moore, K.L. (1992) Clinically Oriented Anatomy. 3rd Edition, Williams and Wilkins, Philadelphia.
[4] Harris, A., Kamishima, T., Hao, H.Y., Kato, F., et al. (2010) Splenic Volume Measurements on Computed Tomography Utilizing Automatically Contouring Software and Its Relationship with Age, Gender, and Anthropometric Parameters. European Journal of Radiology, 75, 97-101.
http://dx.doi.org/10.1016/j.ejrad.2009.08.013
[5] Rodrigues Junior, A.J., Rodrigues, C.J., Germano, M.A., Rasera Junior, I. and Cerri, G.G. (1995) Sonographic Assessment of Normal Spleen Volume. Clinical Anatomy, 8, 252-255.
http://dx.doi.org/10.1002/ca.980080403
[6] Spielmann, A.L. DeLong, D.M. and Kliewer, M.A. (2005) Sonographic Evaluation of Spleen Size in Tall Healthy Athletes. American Journal of Roentgenology, 184, 45-49.
http://dx.doi.org/10.2214/ajr.184.1.01840045
[7] Zhang, B. and Lewis, S.M. (1987) Use of Radionuclide Scanning to Estimate Size of Spleen in Vivo. Journal of Clinical Pathology, 40, 508-511. http://dx.doi.org/10.1136/jcp.40.5.508
[8] Niederau, C., Sonnenberg, A. and Muller, J.E. (1983) Sonographic Measurements of the Normal Liver, Spleen, Pancreas, and Portal Vein. Radiology, 149, 537-540.
[9] Friis, H., Ndhlovu, P., Mduluza, T., Kaondera, K., Franke, D., Vennervald, B.J., et al. (1996) Ultrasonographic Organometry: Liver and Spleen Dimensions among Children in Zimbabwe. Tropical Medicine & International Health, 1, 183-190. http://dx.doi.org/10.1111/j.1365-3156.1996.tb00024.x
[10] Hidaka, H., Nakazawa, T., Wang, G., et al. (2010) Reliability and Validity of Splenic Volume Measurement by 3-D Ultrasound. Hepatology Research, 40, 979-988.
http://dx.doi.org/10.1111/j.1872-034X.2010.00705.x
[11] Ishibashi, H., Higuchi, N., Shimamura, R., Hirata, Y., Kudo, J. and Niho, Y. (1991) Sonographic Assessment and Grading of Spleen Size. Journal of Clinical Ultrasound, 19, 21-25.
http://dx.doi.org/10.1002/jcu.1870190106
[12] Rosenberg, H.K., Markowitz, R.I., Kolberg, H., Park, C., Hubbard, A. and Bellah, R.D. (1991) Normal Splenic Size in Infants and Children: Sonographic Measurements. American Journal of Roentgenology, 157, 119-121.
http://dx.doi.org/10.2214/ajr.157.1.2048509
[13] Pietri, H. and Boscaini, M. (1984) Determination of a Splenic Volumetric Index by Ultrasonic Scanning. Journal of Ultrasound in Medicine, 3, 19-23.
[14] Henderson, J.M., Heymsfield, S.B., Horowitz, J. and Kutner, M.H. (1981) Measurement of Liver and Spleen Volume by Computed Tomography. Radiology, 141, 525-527.
[15] Hoefs, J.C., Wang, F.W., Lilien, D.L., Walker, B. and Kanel, G. (1999) A Novel, Simple Method of Functional Spleen Volume Calculation by Liver-Spleen Scan. Journal of Nuclear Medicine, 40, 1745-1755.
[16] Frank, K., Linhart, P., Kortsik, C. and Wohlenberg, H. (1986) Sonographic Determination of Spleen Size: Normal Dimensions in Adults with a Healthy Spleen. Ultraschall in der Medizin, 7, 134-137.
http://dx.doi.org/10.1055/s-2007-1011931
[17] Dittrich, M., Milde, S., Dinkel, E., Baumann, W. and Weitzel, D. (1983) Sonographic Biometry of Liver and Spleen Size in Childhood. Pediatric Radiology, 13, 206-211.
http://dx.doi.org/10.1007/BF00973157
[18] Mazonakis, M., Damilakis, J., Maris, T., Prassopoulos, P. and Gourtsoyiannis, N. (2000) Estimation of Spleen Volume Using MR Imaging and a Random Marking Technique. European Radiology, 10, 1899-1903.
http://dx.doi.org/10.1007/s003300000551
[19] Al-Imam, O., Suleiman, A. and Khuleifat, S. (2000) Ultrasound Assessment of Normal Splenic Length and Spleen-To-Kidney Ratio in Children. Eastern Mediterranean Health Journal, 6, 514-516.
[20] Konus, O.L., Ozdemir, A., Akkaya, A., Erbas, G., Celik, H. and Isik, S. (1998) Normal Liver, Spleen, and Kidney Dimensions in Neonates, Infants, and Children: Evaluation with Sonography. American Journal of Roentgenology, 171, 1693-1698. http://dx.doi.org/10.2214/ajr.171.6.9843315
[21] Prassopoulos, P., Daskalogiannaki, M., Raissaki, M., Hatjidakis, A. and Gourtsoyiannis, N. (1997) Determination of Normal Splenic Volume on Computed Tomography in Relation to Age, Gender and Body Habitus. European Radiology, 7, 246-248. http://dx.doi.org/10.1007/s003300050145
[22] Mittal, R. and Chowdhary, D.S. (2010) A Pilot Study of the Normal Measurements of the Liver and Spleen by Ultrasonography in the Rajasthani Population. Journal of Clinical and Diagnostic Research, 4, 2733-2736.
[23] Breiman, R.S., Beck, J.W. and Korobkin, M. (1982) Volume Determinations Using Computed Tomography. American Journal of Roentgenology, 138, 329-333.
http://dx.doi.org/10.2214/ajr.138.2.329
[24] Haddad-Zebouni, S., Hindy, R., Slaba, S., Aoun, N., Mourani, C., Abi Ghanem, S., et al. (1999) Ultrasonographic Evaluation of the Kidney, Liver and Spleen Size in Children. Archives of Pediatrics, 6, 1266-1270.
http://dx.doi.org/10.1016/S0929-693X(00)88887-9
[25] Loftus, W.K., Chow, L.T.C. and Metreweli, C. (1999) Sonographic Measurement of Splenic Length: Correlation with Measurement at Autopsy. Journal of Clinical Ultrasound, 27, 71-74.
http://dx.doi.org/10.1002/(SICI)1097-0096(199902)27:2<71::AID-JCU4>3.0.CO;2-U
[26] Loftus, W.K. and Metreweli, C. (1997) Normal Splenic Size in a Chinese Population. Journal of Ultrasound in Medicine, 16, 345-347.
[27] Yetter, E.M., Acosta, K.B., Olson, M.C. and Blundell, K. (2003) Estimating Splenic Volume: Sonographic Measurements Correlated with Helical CT Determination. American Journal of Roentgenology, 181, 1615-1620.
http://dx.doi.org/10.2214/ajr.181.6.1811615
[28] Mustapha, Z., Tahir, A., Tukur, M., Bukar, M. and Lee, W.K. (2010) Sonographic Determination of the Normal Spleen Size in an Adult African Population. European Journal of Radiology, 75, 133-135.
http://dx.doi.org/10.1016/j.ejrad.2009.09.025
[29] Asghar, A., Agrawal, D., Yunus, S.M., Sharma, P.K., Zaidi, S.H.H. and Sinha, A. (2011) Standard Splenic Volume Estimation in North Indian Adult Population: Using 3D Reconstruction of Abdominal CT Scan Images. Anatomy Research International, 2011, 5 p.

  
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