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Natural Antimicrobial Peptides: Pleiotropic Molecules in Host Defense

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DOI: 10.4236/cellbio.2013.24023    4,299 Downloads   7,395 Views   Citations

ABSTRACT

Natural antimicrobial peptides (AMPs) are small cationic molecules that display antimicrobial activity against a wide range of bacteria, fungi and viruses. AMPs are multifunctional molecules that have an essential activity in infection and inflammation: they play an important role in the innate immune response, not only as antimicrobial agents, but also as immunomodulating molecules and as an important link between the innate and adaptive immune response. In this article, we will discuss the antimicrobial activity, together with the novel properties of some of these molecules as immune modulators on the innate and adaptive immune response.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

M. Leonor Sánchez, M. María Belén Martínez and P. César Maffia, "Natural Antimicrobial Peptides: Pleiotropic Molecules in Host Defense," CellBio, Vol. 2 No. 4, 2013, pp. 200-210. doi: 10.4236/cellbio.2013.24023.

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