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Symptom overlap between schizophrenia and bipolar mood disorder: Diagnostic issues

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DOI: 10.4236/ojpsych.2013.34A002    4,138 Downloads   7,168 Views   Citations

ABSTRACT

Although the Kraepelinian classification paradigm is widely used, observations of overlapping boundaries among the symptoms associated with bipolar disorder and schizophrenia are beginning to challenge this dichotomy. The objective of this research was to explore the symptoms of individuals diagnosed with schizophrenia and with bipolar mood disorder in order to determine the frequency of symptom overlap. One hundred patients of a psychiatry ward were divided into two main groups based on their diagnosis—schizophrenia or bipolar mood disorder. Chi-square analyses were used to determine whether the symptoms measured in this study differed between individuals diagnosed with schizophrenia and those diagnosed with bipolar mood disorder. The results suggest that both positive/manic symptoms and negative/depressive symptoms are present in individuals diagnosed with schizophrenia and with bipolar mood disorder and, consequently, they do not present a reliable means of differentiating between these two groups. These findings have many implications for the ways in which mental illness is conceptualized and classified. Treatment efforts and interventions may be enhanced if a more dimensional approach to diagnosing mental illness is utilized.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Bambole, V. , Johnston, M. , Shah, N. , Sonavane, S. , Desouza, A. and Shrivastava, A. (2013) Symptom overlap between schizophrenia and bipolar mood disorder: Diagnostic issues. Open Journal of Psychiatry, 3, 8-15. doi: 10.4236/ojpsych.2013.34A002.

References

[1] Kraepelin, E., (1919) Dementia praecox and paraphrenia. Chicago Medical Book Co., Chicago.
[2] Kendler, K.S., Karkowski, L.M. and Walsh, D. (1998) The structure of psychosis: Latent class analysis of probands from the Roscommon Family Study. Archives of General Psychiatry, 55, 492-509. http://dx.doi.org/10.1001/archpsyc.55.6.492
[3] Craddock, N., O’Donovan, M.C. and Owen, M.J. (2006) Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophrenia Bulletin, 32, 9-16. http://dx.doi.org/10.1093/ schbul/sbj033
[4] Ivleva, E., Thaker, G. and Tamminga, C.A. (2008) Comparing genes and phenomenology in the major psychoses: Schizophrenia and bipolar 1 disorder. Schizophrenia Bulletin, 34, 734-742.
http://dx.doi.org/10.1093/schbul/sbn051
[5] Chen, Y.R., Swann, A.C. and Johnson, B.A. (1998) Stability of diagnosis in bipolar disorder. Journal of Nervous & Mental Disease, 186, 17-23. http://dx.doi.org/10.1097/00005053-199801000-00004
[6] Singh, S.P., Croudace, T., Amin, S., Kwiecinski, R., Medley, I., Jones, P.B. and Harrison, G. (2000) Threeyear outcome of first-episode psychoses in an established community psychiatric service. British Journal of Psychiatry, 176, 210-216. http://dx.doi.org/10.1192/bjp.176.3.210
[7] Cardno, A.G., Rijsdijk, F.V., Sham, P.C., Murray, R.M. and McGuffin, P. (2002) A twin study of genetic relationships between psychotic symptoms. American Journal of Psychiatry, 159, 539-545. http://dx.doi.org/10.1176/appi.ajp.159.4.539
[8] Sim, K., Swapna, V., Mythily, S., Mahendran, R., Kua, E.H., McGorry, P. and Chong, S.A. (2004) Psychiatric co-morbidity in the first episode of psychosis: The Early Psychosis Intervention Program (EPIP) experience. Acta Psychiatrica Scandinavica, 109, 23-29. http://dx.doi.org/10.1111/j.0001-690X.2004.00196.x
[9] Hafner, H., Maurer, K., Trendler, G., an der Heiden, W., Schmidt, M. and Konnecke, R. (2005) Schizophrenia and depression: Challenging the paradigm of two separate diseases—A controlled study of schizophrenia, depression and healthy controls. Schizophrenia Research, 77, 11-24. http://dx.doi.org/10.1016/j.schres.2005.01.004
[10] Romm, K.L., Rossberg, J.I., Berg, A.O., Barrett, E.A., Faerden, A., Agartz, I., Andreassen, O.A. and Melle, I. (2010) Depression and depressive symptoms in first episode psychosis. Journal of Nervous & Mental Disease, 198, 67-71. http://dx.doi.org/10.1097/NMD.0b013e3181c81fc0
[11] Johnson, J., Horwath, E. and Weissman, M.M. (1991) The validity of major depression with psychotic features based on a community study. Archives of General Psychiatry, 48, 1075-1081. http://dx.doi.org/10.1001/archpsyc.1991.01810360039006
[12] Schatzberg, A.F. and Rothschild, A.J. (1992) Psychotic (delusional) major depression: Should it be included as a distinct syndrome in DSM-IV? American Journal of Psychiatry, 149, 733-745
[13] Kasanin, J. (1933) The acute schizoaffective psychoses. American Journal of Psychiatry, 90, 97-126.
[14] Heckers, S. (2009) Is schizoaffective disorder a useful diagnosis? Current Psychiatry Reports, 11, 332-337. http://dx.doi.org/10.1007/s11920-009-0048-3
[15] Andreasen, N.C. (1984) The Scale for the assessment of Positive Symptoms (SAPS). The University of Iowa, Iowa City.
[16] Andreasen, N.C. (1983) The Scale for the Assessment of Negative Symptoms (SANS). The University of Iowa, Iowa City.
[17] Hamilton, M. (1960) A rating scale for depression. Journal of Neurology, Neurosurgery & Psychiatry, 23, 56-62. http://dx.doi.org/10.1136/jnnp.23.1.56
[18] Young, R.C., Biggs, J.T., Ziegler, V.E. and Meyer, D.A. (1978) A rating scale for mania: Reliability, validity and sensitivity. British Journal of Psychiatry, 133, 429-435. http://dx.doi.org/10.1192/bjp. 133.5.429
[19] Dratcu, L. and Cali, H.M. (1989) The dexamethasone suppression test: Its relationship to diagnoses, severity of depression and response to treatment. Progress in NeuroPsychopharmacology & Biological Psychiatry, 13, 99-117. http://dx.doi.org/10.1016/0278-5846(89)90007-9

  
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