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Barrier, Adsorptive, and Mechanical Properties of Containers Molded from PET/PP Blends for Use in Pharmaceutical Solutions

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DOI: 10.4236/msa.2013.410072    3,696 Downloads   5,430 Views   Citations

ABSTRACT

In this study, the adsorptive properties of L-menthol, moisture vapor transmission rate, and mechanical properties of poly (ethylene terephthalate) (PET), polypropylene (PP), and their blends were evaluated in containers fabricated by injection molding without a compatibilizing agent. These containers intended to hold pharmaceutical solutions containing lipophilic chemicals such as L-menthol. By the addition of a small amount of PP, the moisture barrier properties of PET were effectively improved, but its anti-adsorptive property was reduced. The strength of the PET/PP blends was reduced, but some PET/PP blends were still able to bear the experimental load required for application in eye-drop containers. PET/PP = 9/1 and PET/PP = 8/2 were found to be most applicable for using in the fabrication of containers for medicinal solutions.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

T. Otsuka, A. Kurosawa, M. Maeda, K. Yamada, M. Murakami and H. Hamada, "Barrier, Adsorptive, and Mechanical Properties of Containers Molded from PET/PP Blends for Use in Pharmaceutical Solutions," Materials Sciences and Applications, Vol. 4 No. 10, 2013, pp. 589-594. doi: 10.4236/msa.2013.410072.

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