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Necrotizing Scleritis Associated with 5-Fluorouracil and Sub-Tenon’s Block in Patient with Previous Trabeculectomy: A Case Report

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DOI: 10.4236/ojoph.2013.33018    2,747 Downloads   3,696 Views  


Necrotizing scleritis is the most severe form of scleritis with a significant threat to vision and globe integrity. It can be infectious, surgically induced necrotizing scleritis (SINS) or systemic autoimmune associated. We report a case of necrotizing scleritis associated with 5-fluorouracil (5-FU) at the site of sub tenon’s block in a patient with previous trabeculectomy. To our knowledge, this is the first reported case of necrotizing scleritis associated with 5-FU. This may implicate alternative approaches to local anaesthetic techniques when using adjunctive 5-FU.

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The authors declare no conflicts of interest.

Cite this paper

T. Tran, J. O’Connor, X. Fagan, T. Tran and D. Nguyen, "Necrotizing Scleritis Associated with 5-Fluorouracil and Sub-Tenon’s Block in Patient with Previous Trabeculectomy: A Case Report," Open Journal of Ophthalmology, Vol. 3 No. 3, 2013, pp. 73-75. doi: 10.4236/ojoph.2013.33018.


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