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Synthesis and Enhanced Guest-Binding Affinities of Dendrimer-Based Cyclophane Tetramer and Octamer

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DOI: 10.4236/aces.2013.33A1004    3,842 Downloads   5,563 Views   Citations

ABSTRACT

Dendritic cyclophane tetramer and octamer were prepared by aminolysis of succinimidyl ester derivative of tetraaza [6.1.6.1] paracyclophane with the corresponding poly(amidoamine) dendrimers as a scaffold, followed by removal of the protecting groups. The present cyclophane tetramer and octamer showed enhanced guest-binding affinities toward fluorescent guests such as 6-p-toluidinonaphthalene-2-sulfonate and 6-anilinonaphthalene-2-sulfonate, in comparison with those of monocyclic cyclophane, reflecting multivalency effects in macrocycles.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

O. Hayashida, T. Nakashima and Y. Kaku, "Synthesis and Enhanced Guest-Binding Affinities of Dendrimer-Based Cyclophane Tetramer and Octamer," Advances in Chemical Engineering and Science, Vol. 3 No. 3A, 2013, pp. 33-37. doi: 10.4236/aces.2013.33A1004.

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