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Long Lasting Efficiency of Monthly Vinblastine in a Case of Relapsed Anaplastic Large Cell Lymphoma

DOI: 10.4236/ojbd.2013.32013    2,680 Downloads   4,369 Views   Citations

ABSTRACT

Nearly 40% of children with Anaplastic Large cell lymphomas will relapse after a first-line strategy with short-pulse chemotherapy and reach a second remission in 30% to 60% with second line therapies including maintenance treatment with vinblastine or allogeneic hematopoietic stem-cell transplantation. The authors report a heavily pretreated case in second relapse who was maintained in third remission for 8 years with monthly vinblastine. He relapsed 16 weeks after discontinuation. This case demonstrates that monthly treatment with vinblastine may be sufficient to maintain a minimal disease. Oral compounds are now available and should be discussed in such situations.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

R. Mlis, M. Schell, P. Bérard, N. Bleyzac and D. Frappaz, "Long Lasting Efficiency of Monthly Vinblastine in a Case of Relapsed Anaplastic Large Cell Lymphoma," Open Journal of Blood Diseases, Vol. 3 No. 2, 2013, pp. 63-64. doi: 10.4236/ojbd.2013.32013.

References

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