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Decreasing serum uric acid levels are associated with improving estimated glomerular filtration rate (eGFR) in Japanese women

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DOI: 10.4236/ojepi.2013.32007    3,276 Downloads   4,945 Views  

ABSTRACT

The aim of this study was to investigate the link between changes in a subject’s serum uric acid levels and the estimated glomerular filtration rate (eGFR) in Japanese women. We used data for 161 Japanese women (49.8 ± 11.7 years) with a 1-year follow up. eGFR was defined by a new equation developed for Japan. eGFR was negatively correlated with serum uric acid levels (r = -0.402, p < 0.0001) at baseline. Subjects were given advice for dietary and lifestyle improvement. At the 1-year follow up, abdominal circumference and systolic blood pressure (SBP) were significantly improved. However, uric acid and eGFR did not change. The changes in eGFR were negatively correlated with uric acid (r = -0.475, p < 0.0001). A decrease in serum uric acid levels was associated with improving eGFR in Japanese women.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Miyatake, N. , Shikata, K. , Makino, H. and Numata, T. (2013) Decreasing serum uric acid levels are associated with improving estimated glomerular filtration rate (eGFR) in Japanese women. Open Journal of Epidemiology, 3, 40-43. doi: 10.4236/ojepi.2013.32007.

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