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Gene Expression Profile, Androgen Independence and Prostate Cancer

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DOI: 10.4236/jct.2012.35082    3,833 Downloads   5,766 Views   Citations

ABSTRACT

It is now generally accepted that the burden of disease due to prostate cancer has tremendously increased globally. Current data indicates that prostate cancer is the most common form of cancer in men in the United State of America, and the second leading cause of death due to cancer in men. Progression to androgen independence and subsequent therapeutic resistance and death is a common fate of patients with prostate cancer. This review highlights the gene expression profile of androgen independent prostate cancer and the possible mechanisms that results in transformation to such treatment resistant state.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

M. Omabe, J. C. Onyeanusi, N. Amos, M. Ezeani and S. Imakwu Okekpa, "Gene Expression Profile, Androgen Independence and Prostate Cancer," Journal of Cancer Therapy, Vol. 3 No. 5, 2012, pp. 637-644. doi: 10.4236/jct.2012.35082.

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