Share This Article:

Vogt-Koyanagi-Harada syndrome associated to hypothyroidism revealed by myocarditis

Abstract Full-Text HTML XML Download Download as PDF (Size:54KB) PP. 176-178
DOI: 10.4236/ojim.2012.23027    3,191 Downloads   5,431 Views  

ABSTRACT

Purpose: Vogt-Koyanagi-Harada (VKH) syndrome is usually defined as an uveo-meningitis who may be associated with auditory and cutaneous signs. Association of VKH syndrome and autoimmune thyroiditis is uncommon. Observation: A 28-year-old man was admitted with thoracic pain due to myocarditis. Two years ago he presented VKH syndrome with specific ocular manifestation and deafness, treated by corticosteroids and immunosuppressive. Etiologic investigation of myocarditis concluded to deep hypothyroidism related to Hashimoto thyroiditis. The patient improved after substitutive treatment by thyroid hormones. Conclusion: Thyroid function should be systematically investigated in case of VKH syndrome and particularly when associated to dysthyroidism symptoms.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Ismail, F. , Mzabi, A. , Karmani, M. , Rezgui, A. , Mhiri, H. and Laouani-Kechrid, C. (2012) Vogt-Koyanagi-Harada syndrome associated to hypothyroidism revealed by myocarditis. Open Journal of Internal Medicine, 2, 176-178. doi: 10.4236/ojim.2012.23027.

References

[1] Guenoun JM, Parc C, Dhote R, Brezin AP. Le syndrome de Vogt-Koyanagi-Harada: aspects cliniques, traitement et suivi à long terme dans une population caucasienne et africaine. J Fr Ophtalmol 2004 ; 27(9):1013-6
[2] Alaoui FZ, Benamour S, El Kabli H, Amraoui A. Syndrome de Vogt-Koyanagi-Harada. A propos de huit cas. Rev Med Inter 2007;46:250-4
[3] Damico FM, da Silva FT, Gasparin F, Yamamoto JH. New insights into Vogt-Koyanagi-Harada disease. Arq Bras Ophtalmol 2009; 72:413-20
[4] Wiesli P, Bernauer W, Furrer J. Headache and bilateral visual loss in a young hypothyroid Indian man. J Endocrinol Invest 1999; 22:141-3
[5] Jaggarao N, Voth D, Jacobsen J. The Vogt-Koyanagi-Harada syndrome: association with hypothyroid- dism and diabetes mellitus. Postgrad Med J 1989; 65(766):587-8
[6] Kluger N, Mura F, Guillot B, Bessis D. Vogt-Koyanagi-Harada syndrome Associated with Psoriasis and Autoimmune Thyroid Disease. Acta Derm Venereol 2008; 88 (4):397-8
[7] Chi HI, Furue M, Ishibashi Y. Vogt-Koyanagi-Harada’s syndrome associated with Hashimoto’s thyroiditis. J Dermatol 1994; 21: 683–686.
[8] Paroli MP, Pinca M, Speranza S, Marino M, Pivetti-Pezzi P. Paracentral corneal melting in a patient with Vogt- Koyanagi-Harada’s syndrome, psoriasis, and Hashimoto’s thyroiditis. Ocul Immunol Inflamm 2003; 11: 309 –313.
[9] Seo JH, Yu HG, Chung H. A case of Vogt-Koya-nagi-Harada disease in a patient with Graves disease. Korean J Ophtalmol 2009; 23:112-3.
[10] Jovic NS, Nesovic M, Vranjesevic DN, Ciric J, Marinkovic DM, Bonaci B. The Vogt-Koyanagi-Harada syndrome: association with autoimmune polyglandular syndrome type 1. Postgrad Med J 1996;72: 495–497.
[11] Duron F, Dubosclard E, Johanet C. Thyro?dites. EMC Endocrinologie 2004, 3-18
[12] Guillevin L, Scheuble C, Attali JR, Modigliani E, Sebaoun J. Etude échocardiographique des hypothyro?dies. Rev Med Intern 1981; 2:187-194
[13] Lorin De La Grandmaison G, Izembart M, Fornes P, Paraire F. Myocarditis associated with Hashimoto's disease: a case report. Int J Legal Med 2003;117:361-4.

  
comments powered by Disqus

Copyright © 2019 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.