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Potentials of Melastoma malabathricum Linn. Flower and Fruit Extracts as Antimicrobial Infusions

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DOI: 10.4236/ajps.2012.38136    4,619 Downloads   8,439 Views   Citations


Melastoma malabathricum Linn. is a shrub that belongs to the family Melastomataceae and a common herbal plant used in folk medicines to treat inflamed wounds. This study was carried out with the aim to evaluate the inhibitory activities of different concentrations of the M. malabathricum Linn. flower and fruit crude extracts against a variety of microorganisms. The inhibitory effects of both extracts were tested against the microorganisms using the disc diffusion method. The lowest concentrations of the extracts producing inhibition zones against the test microorganisms were used to determine their Minimum Inhibitory Concentrations (MICs) and Minimum Microbicidal Concentrations (MMCs). Both crude extracts showed strong inhibitory activities against Gram-positive bacteria. The range of MIC values for the crude flower and fruit extracts on all the bacteria tested were 12.5 to 100.0 mg/ml. Overall, Gram-positive bacteria were more susceptible to the crude extracts compared to Gram-negative species, potentiating a possible use of the extracts to inhibit or kill potential pathogens.

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S. Omar, J. Abdullah, K. Khairoji, S. Chin and M. Hamid, "Potentials of Melastoma malabathricum Linn. Flower and Fruit Extracts as Antimicrobial Infusions," American Journal of Plant Sciences, Vol. 3 No. 8, 2012, pp. 1127-1134. doi: 10.4236/ajps.2012.38136.


[1] World Health Organization (WHO), “National Policy on Traditional Medicine and Regulation of Herbal Medicines,” Geneva, 2005.
[2] B. Bhattacharyya and B. M. Johri, “Flowering Plants: Taxonomy and Phylogeny,” Nurosa Publishing House, New Delhi, 1998.
[3] D. Susanti, M. S. Hasnah, A. Farediah, M. A. Rasadah, A. Norio and K. Mariko, “Antioxidant and Cytotoxicity Flavonoids from the Flowers of Melastoma malabathricum L.,” Food Chemistry, Vol. 103, No. 3, 2007, pp. 710-716. doi:10.1016/j.foodchem.2006.09.011
[4] J. B. Lowry, “Anthocyanins of the Melastomataceae, Myrtaceae and Some Allied Families,” Phytochemistry, Vol. 15, No. 4, 1976, pp. 513-516. doi:10.1016/S0031-9422(00)88960-8
[5] S. M. Jofrry, N. J. Yob, M. S. Rofiee, M. M. R. Meor Mohd. Affandi, Z. Suhaili, F. Othman, M. A. Abdah, M. N. M. Desa and Z. A. Zakaria, “Melastoma malabathricum (L.) Smith Ethnomedicinal Uses, Chemical Constituents, and Pharmacological Properties: A Review,” Evidence-Based Complementary and Alternative Medicine, Vol. 2012, 2011, p. 48.
[6] F. Lohézic-Le Dévéhat, A. Bakhtiar, C. Bézivin, M. Amoros and J. Boustie, “Antiviral and Cytotoxic of Some Indonesian Plants,” Fitoterapia, Vol. 73, No. 5, 2002, pp. 400-405. doi:10.1016/S0367-326X(02)00125-9
[7] Z. A. Zakaria, R. N. R. Mohd. Nor, G. H. Kumar, Z. D. F. Abdul Ghani, M. R. Sulaiman, G. R. Devi, A. M. Mat Jais, M. N. Somchit and C. A. Fatimah, “Antinociceptive, Anti-Inflammatory and Antipyretic Properties of Melastoma malabathricum Leaves Aqueous Extract in Experimental Animals,” Canadian Journal of Physiology Pharmacology, Vol. 84, No. 12, 2006, pp. 1291-1299. doi:10.1139/y06-083
[8] F. Hussain, M. A. Abdulla, S. M. Noor, S. Ismail and H. M. Ali, “Gastroprotective Effects of Melastoma malabathricum Aqueous Leaf Extract Against Ethanol-Induced Gastric Ulser Iin Rats,” American Journal of Biochemistry and Biotechnology, Vol. 4, No. 4, 2008, pp. 438-441. doi:10.3844/ajbbsp.2008.438.441
[9] M. Zulaikah, I. Nazliana and I. B. Ahmad, “Penindasan Terpilih Gen-Gen Staphylococcus aureus Rintang Metisilin Yang Dirawat Dengan Ektrak Metanol Melastoma malabathricum,” Sains Malaysiana, Vol. 37, No. 1, 2008, pp. 107-113.
[10] National Committee for Clinical Laboratory Standard (NCCLS), “Performance Standards for Antimicrobial Susceptibility Testing,” Twelfth International Supplement, M100-S12, Wayne, 2002.
[11] M. E. Arias, J. D. Gomez, N. M. Cudmani, M. A. Vattuone and M. I. Isla, “Antibacterial Activity of Ethanolic and Aqueous Extracts of Acacia aroma Gill. ex Hook et Arn,” Life Sciences, Vol. 75, No. 2, 2004, pp. 191-202. doi:10.1016/j.lfs.2003.12.007
[12] S. M. R. Rohani, M. Moradi, T. Mehdizadeh, S. S. Saei-Dehkordi and M. W. Griffiths, “The Effect of Nisin and Garlic (Allium sativum L.) Essential Oil Separately and in Combination on the Growth of Listeria monocytogenes,” LWT—Food Science and Technology, Vol. 44, 2011, pp. 2260-2265.
[13] B. B. Li, B. Smith and M. M. Hossain, “Extraction of Phenolics from Citrus Peels: I. Solvent Extraction Method,” Separation and Purification Technology, Vol. 48, No. 2, 2006, pp. 182-188. doi:10.1016/j.seppur.2005.07.005
[14] V. Duraipandiyan and S. Ignacimuthu, “Antibacterial and Antifungal Activity of Cassia fistula L.: An Ethnomedicinal Plant,” Journal of Ethnopharmacology, Vol. 112, No. 3, 2007, pp. 590-594. doi:10.1016/j.jep.2007.04.008
[15] L. J. Shai, L. J. McGaw, P. Masoko and J. N. Eloff, “Antifungal and Antibacterial Activity of Seven Traditionally Used South African Plant Species Active against Candida albicans,” South African Journal of Botany, Vol. 74, No. 4, 2008, pp. 677-684. doi:10.1016/j.sajb.2008.04.003
[16] T. P. T. Cushnie and A. J. Lamb, “Antimicrobial Activity of Flavonoids,” International Journal of Antimicrobial Agents, Vol. 26, No. 5, 2005, pp. 343-356. doi:10.1016/j.ijantimicag.2005.09.002
[17] Y.-C. Wang, H.-W. Hsu and W.-L. Liao, “Antibacterial Activity of Melastoma candidum D. Don,” LWT—Food Science and Technology, Vol. 41, No. 10, 2008, pp. 1793-1798.
[18] H. N. Thatoi, S. K. Panda, S. K. Rath and S. K. Dutta, “Antimicrobial Activity and Ethnomedicinal Uses of Some Medicinal Plants from Similipal Biosphere Reserve, Orissa,” Asian Journal of Plant Sciences, Vol. 7, No. 3, 2008, pp. 260-267. doi:10.3923/ajps.2008.260.267
[19] P. W. Grosvenor, A. Supriono and D. O. Gray, “Medicinal Plants from Riau Province, Sumatra, Indonesia. Part 2: Antibacterial and Antifungal Activity,” Journal of Ethnopharmacology, Vol. 45, No. 2, 1995, pp. 97-111. doi:10.1016/0378-8741(94)01210-Q
[20] B. Shan, Y.-Z. Cai, J. D. Brooks and H. Corke, “The in Vitro Antibacterial Activity of Dietary Spice and Medical Herbs Extracts,” International Journal of Food Microbiology, Vol. 117, No. 1, 2007, pp. 112-119. doi:10.1016/j.ijfoodmicro.2007.03.003
[21] E. Cheylan and D. Y. C. Fung, “Antimicrobial Activity of Spices,” Journal of Rapid Method and Automation in Microbiology, Vol. 12, No. 1, 2004, pp. 1-55. doi:10.1111/j.1745-4581.2004.tb00046.x
[22] P. Lopez, C. Sanchez, R. Batlle and C. Nerin, “Solid- and Vapor-Phase Antimicrobial Activities of Six Essential Oils: Susceptibility of Selected Foodborne Bacteria and Fungal Strains,” Journal of Agriculture and Food Chemistry, Vol. 53, No. 17, 2005, pp. 6939-6946. doi:10.1021/jf050709v
[23] C. F. Duffy and R. F. Power, “Antioxidant and Antimicrobial Properties of Some Chinese Plant Extracts,” International Journal of Antimicrobial Agents, Vol. 17, No. 6, 2001, pp. 527-529.
[24] Y. Gao, M. J. Van Belkum and M. E. Stiles, “The Outer Membrane of Gram-Negative Bacteria Inhibits Antibacterial Activity of Brochocin-C,” Applied and Environmental Microbiology, Vol. 65, No. 10, 1999, pp. 4329-4333.
[25] J. C?té, S. Caillet, G. Doyon, D. Dussault, J.-F. Sylvain and M. Lacroix, “Antimicrobial Effect of Cranberry Juice and Extracts,” Food Control, Vol. 22, No. 8, 2011, pp. 1413-1418. doi:10.1016/j.foodcont.2011.02.024
[26] T. Taguri, T. Tanaka and I. Kouno, “Antimicrobial Activity of 10 Different Plant Polyphenols against Bacteria Causing Food-Borne Disease,” Biological and Pharmaceutical Bulletin, Vol. 27, No. 12, 2004, pp. 1965-1969. doi:10.1248/bpb.27.1965
[27] A. Basile, S. Sorbo, S. Giordano, L. Ricciardi, S. Ferrara, D. Montesano, R. C. Cobianchi, M. L. Vuotto and L. Ferrara, “Antibaterial and Allelopathic Activity of Extract from Castanea sativa Leaves,” Fitoterapia, Vol. 71, No. 1, 2000, pp. S110-S116. doi:10.1016/S0367-326X(00)00185-4

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