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Use of antidepressants in diabetes patients not using drugs, but only monitoring blood glucose

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DOI: 10.4236/jdm.2012.22037    2,750 Downloads   4,599 Views  

ABSTRACT

Objective: Patients with diabetes have an increased Odds Ratio (OR) for depressive disor- der. We wanted to investigate if patients with metabolic syndrome and/or diabetes type 2 not treated with antidiabetic agents, have an OR for concurrent antidepressant use comparable to other types of diabetes. Methods: Drug delivery data from 25 pharmacies were analysed with respect to sale of antidepressants, oral antidiabetic agents, insulin and blood glucose test strips. Results: Total population of the area was 337,019, whereas 254,083 were 18 or older. Of these 20,139 were patients receiving insulin, oral antidiabetics, glucose test strips and/or antidepressants. Those receiving antidepressants were 5.8% of those 18 or older whereas 2.4% received any antidiabetic medication (including test strips for HBGM). For patients receiving no medications but test strips alone, the adjusted OR for use concurrent use of antidepressants was 1.62 (95% confidence interval: 1.19 - 2.23), p = 0.002. For insulin-only receiving patients, the adjusted OR was 1.65 (1.41 - 1.93), p = 0.000, whereas for patients receiving only oral antidiabetics, it was 1.53 (1.38 - 1.71), p = 0.000. Patients receiving both insulin and oral antidiabetics: 2.23 (1.75 - 2.85), p = 0.000. Conclusion: Patients receiving only blood glucose strips have an OR of concurrently receiving antidepressants, not different from those receiving insulin only or oral antidiabetics only.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Hundal, Ø. , Biringer, E. , Losnegard, I. and Lund, A. (2012) Use of antidepressants in diabetes patients not using drugs, but only monitoring blood glucose. Journal of Diabetes Mellitus, 2, 234-237. doi: 10.4236/jdm.2012.22037.

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