Lead poisoning due to geophagia: The consumption of miniature pottery

Abstract

Geophagia (the pica of pottery, clay, earth, or dirt) is practiced before and during pregnancy in several countries, including Mexico, Turkey, Australia, and some African countries, and has been linked with cultural fertility beliefs and the satisfaction of cravings. Unfortunately, consumption of contaminated pottery can represent a source of lead exposure. Concerns regarding ingested pottery are two-fold; first, that people consuming these pots might be exposed to high concentrations of lead, and, second, that ingestion of these pots by pregnant women could result in elevated in utero lead exposure for the fetus. Very few published articles exist on this topic. In an effort to investigate “pot eating”, this study aims to summarize published case studies on lead poisonings resulting from consumption of contaminated pottery. Additionally, several pottery items that are sold for the purpose of consumption were located and analyzed. This paper investigates the risk that “pot eating” poses by reviewing the literature, examining case studies, and analyzing the availability and lead concentration of edible pottery. Preliminary research indicates that although it is not common, “pot eating” can represent a high-risk lead exposure for pregnant women and their fetuses.

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Phipps, A. , Fels, H. , Burns, M. and Gerstenberger, S. (2012) Lead poisoning due to geophagia: The consumption of miniature pottery. Open Journal of Pediatrics, 2, 60-66. doi: 10.4236/ojped.2012.21010.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Smulian, J., Motiwala, S. and Sigman, R. (1995) Pica in rural obstetric population. Southern Medical Journal, 88, 1236-1240. doi:10.1097/00007611-199512000-00010
[2] Derman, O., Okstuz-Kanbur, N., Yenicesy, I. and Klink, E. (2005) Iron deficiency anemia in a group of Turkish adolescents: Frequency and contributing factors. International Journal of Adolescent Medicine and Health, 17, 179-186. doi:10.1515/IJAMH.2005.17.2.179
[3] Hamilton, S., Rothenberg, S., Khan, F., Manalo, M. and Norris, K. (2001) Neonatal Lead Poisoning from maternal pica behavior during pregnancy. Journal of the National Medical Association, 93, 317-319.
[4] MA, A.-K. and Bani, I. (1995) Food habits during pregnancy among Saudi women. International Journal for Vitamin and Nutrition Research, 65, 206-210.
[5] Bateson, E. and Lebroy, T. (1978) Clay eating by aboriginals of the northern territory. Medical Journal of Australia, 1, 1-3.
[6] Eastwell, H. (1979) A pica epidemic: A price for sedentarism among Australian ex-hunter-gatherers. Psychiatry, 42, 264-273.
[7] Edwards, C. (1959) Clay and cornstarch eating women. Journal of the American Dietetic Association, 35, 810- 815.
[8] Bruhn, C. and Panborn, R. (1971) Reported incidence of pica among migrant families. Journal of the American Dietetic Association, 58, 417-420.
[9] Avila, M., Romieu, I., Rios, C., Rivero, A. and Palazuelos, E. (1991) Lead-glazed ceramics as major determinants of blood lead levels in Mexican women. Environmental Health Perspectives, 94, 117-120. doi:10.2307/3431303
[10] Lynch, R., Boatright, D. and Moss, S. (2000) Lead-contaminated imported tamarind candy and children’s blood lead levels. Public Health Reports, 115, 537-543. doi:10.1093/phr/115.6.537
[11] ATSDR (2005) Toxicological profile for lead. http://www.atsdr.cdc.gov/toxprofiles/phs13.html
[12] Rojas-Lopez, M., Santos-Burgoa, C., Rios, C., Hernandez-Avila, M. and Romieu, I. (1994) Use of lead-glazed ceramics is the main factor associated to high lead in blood levels in two Mexican rural communities. Journal of Toxicology and Environmental Health, 42, 45-52.
[13] Rothenberg, S., Manalo, M., Jian, J., Khan, F., Cuellar, R., Reyes, S., et al. (1999) Maternal blood lead level during pregnancy in South Central Los Angeles. Archives of Environmental Health, 54, 151-157.
[14] Donkin, S., Ohlson, D. and Teaf, C. (2000) Properties and effects of metals. In: Williams, P., James, R. and Roberts, S., Eds., Principles of Toxicology, John Wiley & Sons, Inc., New York, 325-344. doi:10.1002/0471231800.ch14
[15] Middendorf, P. and Williams, P. (2000) Nephrotoxicity: Toxic responses of the kidney. John Wiley & Sons, Inc., New York, 139-140.
[16] Bailey, C. and Kitchen, I. (1985) Ontogenesis of proenkephalin products in rat striatum and the Inhibitory effects of low-level lead exposure. Developmental Brain Research, 22, 75-79. doi:10.1016/0165-3806(85)90070-7
[17] Markovac, J. and Goldstein, G. (1988) Picomolar concentrations of lead stimulate brain protein kinase C. Nature, 334, 71-73. doi:10.1038/334071a0
[18] Holtzman, D., DeVries, C., Nguyen, H. and Bensch, K. (1984) Maturation of resistance to lead encephalopathy: Celular and subcellular mechanisms. Neurotoxicology, 5, 97-124.
[19] Needleman H. (2004) Lead poisoning. Annual Review of Medicine, 55, 209-222. doi:10.1146/annurev.med.55.091902.103653
[20] Needleman, H., Schell, A., Bellinger, D., Leviton, A. and Allred, E. (1990) The long-term effects of exposure to low doses of lead in childhood. An 11-year follow-up report. New England Journal of Medicine, 322, 83-88. doi:10.1056/NEJM199001113220203
[21] Rice, D. (1992) Behavioral impairment produced by developmental lead exposure: evidence from primate reseach. In: Needleman, H., Ed., Human Lead Exposure, CRC, Boca Raton.
[22] Manton, W. (1985) Total contribution of airborne lead to blood lead. British Journal of Industrial Medicine, 42, 168-172.
[23] Rothenberg, S., Karchmer, S., Schnaas, L., Perroni, E., Zea, F., Salinas, V., et al. (1996) Maternal influences on cord blood lead levels. Journal of Exposure Analysis and Environmental Epidemiology, 6, 211-227.
[24] Viksna, A. and Lindgren, E. (1997) Determination of lead and cadmium in whole blood of mothers and their babies. Analytica Chimica Acta, 353, 307-311. doi:10.1016/S0003-2670(97)87790-2
[25] Robinson, C., Hall, J. and Beshir, S. (1983) Hormonal modulation of mineral metabolism in reproduction. Proceedings of the Nutrition Society, 42, 169-180. doi:10.1079/PNS19830022
[26] Miller, R. (1983) Perinatal toxicology: Its recognition and fundamentals. American Journal of Industrial Medicine, 4, 205-243. doi:10.1002/ajim.4700040118
[27] Garel, J. (1987) Hormonal control of calcium metabolism during the reproductive cycle in mammals. Physiological Reviews, 67, 1-66.
[28] Purdie, D., Aaron, J. and Selby, P. (1988) Bone histology and mineral homeostasis in human pregnancy. British Journal of Obstetrics and Gynaecology, 95, 849-854. doi:10.1111/j.1471-0528.1988.tb06568.x
[29] Rabinowitz, M. (1990) Toxicokinetics of bone lead. Environmental Health Perspectives, 91, 33-37. doi:10.1289/ehp.919133
[30] Averil, D. and Needleman, H. (1980) Neonatal lead exposure retards cortical synaptogenesis in the rat. In: Needleman, H., Ed., Low Level Lead Exposure: The Clinical Implications of Research, Raven Press, New York, 210-220.
[31] Alexander, F. and Delves, H. (1981) Blood lead levels during pregnancy. International Archives of Occupational and Environmental Health, 48, 35-39. doi:10.1007/BF00405929
[32] Barltrop, D. (1969) Transfer of lead to the human fetus. In: Barland, D., Ed., Mineral Metabolism in Pediatrics, Davis, Philadelphia, 135-151.
[33] Gershanik, J., Brooks, G. and Little, J. (1974) Blood lead levels in pregnant women and their offspring. American Journal of Obstetrics & Gynecology, 119, 508-511.
[34] Borella, P., Picco, P. and Masellis, G. (1986) Lead content in abortion material from urban women in early pregnancy. International Archives of Occupational and Environmental Health, 57, 93-99. doi:10.1007/BF00381376
[35] Graziano, J., Popovac, D., Factor-Litvak, P., Shrout, P., Kline, J., Murphy, M., et al. (1990) Determinants of elevated blood lead during pregnancy in a population surreounding a lead smelter in Kosoud, Yugoslavia. Environmental Health Perspectives, 89, 95-100. doi:10.1289/ehp.908995
[36] Robinson, M., Karpinski, F. and Brieger, H. (1958) The concentration of lead in plasma, whole blood, and erythrocytes of infants and children. Pediatrics, 21, 693.
[37] Newland, M., Yezhou, S., Logdberg, B. and Berlin, M. (2002) Prolonged behavioral effects of in utero exposure to lead or methyl mercury: Reduced sensitivity to changes in reinforcement contingencies during behavioral transitions and in steady state. Toxicology and Applied Pharmacology, 126, 6-15. doi:10.1006/taap.1994.1084
[38] Bellinger, D., Leviton, A. and Sloman, J. (1990) Antecedants and correlates of improved cognitive performance in children exposed in utero to low levels of lead. Environmental Health Perspectives, 89, 5-11. doi:10.1289/ehp.90895
[39] Bellinger, D., Needleman, H., Leviton, A., Waternaux, C., Rabinowitz, M. and Nichols, M. (1984) Early sensory- motor development and prenatal exposure to lead. Neurobehavioral Toxicology & Teratology, 6, 387-402.
[40] Baghurst, P. (1992) Environmental exposure to lead and children’s intelligence at the age of seven years: The port pirie cohort study. New England Journal of Medicine, 327, 1279. doi:10.1056/NEJM199210293271805
[41] Lowry, L., Cherry, D., Brady, C., Huggins, B., D’Sa, A. and Levin, J. (2004) An unexplained case of elevated blood lead in a Hispanic child. Environmental Health Perspectives, 112, 222-225. doi:10.1289/ehp.6486
[42] Mycyk, M. and Leilan, J. (2004) Combined exchange transfusion and chelation therapy for neonatal lead poisoning. The Annals of Pharmacotherapy, 38, 821-824. doi:10.1345/aph.1D475
[43] Erdem, G., Hernandez, X., Kyono, M., Chan-Nishina, C. and Iwaishi, L. (2004) In-utero lead exposure after maternal ingestion of Mexican pottery: Inadequacy of the lead exposure questionnaire. Clinical Pediatrics, 43, 185. doi:10.1177/000992280404300209
[44] Administration UFaD (2000) EAM 4.1 flame atomic absorption spectrometric determination of lead and cadmium extracted from ceramic foodware. FDA Elemental Analysis Manual for Food and Related Products.
[45] Administration UFaD (2004) CPG Sec 545.450 pottery (ceramics); import and domestic—Lead contamination.
[46] Administration UFaD (2000) Action levels for poisonous or deleterious substances in human food and animal feed.

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