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Rothiamucilaginosa life threatening infections in non-neutropenic hosts

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DOI: 10.4236/ojim.2011.13014    7,570 Downloads   14,406 Views   Citations

ABSTRACT

Rothiamucilaginosa, previously known as Stomatococcus mucilaginous, resides in the oral cavity and respiratory tract as part of the normal flora [1]. It is a gram-positive, cocus-shaped bacterium. The bacterium is considered an emerging opportunistic pathogen in patients with chronic immunosuppressive diseases. Most of these reports were described in severe neutropenia or hematological cancer patients but less frequently in immune-competent hosts. We report two cases of endocarditis and meningitis due to R. mucilaginosain non-neutropenic hosts.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Faiad, G. , Singh, M. , Narasimhan, A. , Mendez, M. , Sharma, S. and Nassar, N. (2011) Rothiamucilaginosa life threatening infections in non-neutropenic hosts. Open Journal of Internal Medicine, 1, 68-71. doi: 10.4236/ojim.2011.13014.

References

[1] McWhinney, P.H., Kibbler, C.C., Gillespie, S.H., Patel, S., Morrison, D., Hoffbrand, A.V. and Prentice, H.G. (1992) Stomatococcusmucilaginosus: An emerging pathogen in neutropenic patients. Clinical Infectious Diseases, 14, 641-646. doi:10.1093/clinids/14.3.641
[2] Henwick, S., Koehler, M. and Patrick, C.C. (1993) Complications of bacteremia due to Stomatococcusmucilaginosus in neutropenic children. Clinical Infectious Diseases, 17, 667-671. doi:10.1093/clinids/17.4.667
[3] Gruson, D., Hilbert, G., Pigneux, A., Vargas, F., Guisset, O., Texier, J., Boiron, J.M., Reiffers, J., Gbikpi-Benissan, G. and Cardinaud, J.P. (1998) Severe infection caused by Stomatococcusmucilaginosus in a neutropenic patient: case report and review of the literature. Hematology and Cell Therapy, 40, 167-169.
[4] Van Tiel, F.H., Slangen, B.F., Schouten, H.C. and Jacobs, J.A. (1995) Study of Stomatococcusmucilaginosusiso lated in a hospital ward using phenotypic characterization. European Journal of Clinical Microbiology and Infectious Diseases, 14, 193-198. doi:10.1007/BF02310355
[5] Lee, A.B., Harkery-Murray, P., Ferrieri, P., Schleiss, M.R. and Tolar, J. (2008) Bacterial meningitis from rothiamu-cilaginosa in patients with malignancy or undergoing hematopoietic stem cell transplantation. Pediatric Blood Cancer, 50, 673-676. doi:10.1002/pbc.21286
[6] Mitchell, P.S., Huston, B.J., Jones, R.N., Holcomb, L. and Koontz, F.P. (1990) Stomatococcusmucilaginosusbacteraemias: Typical case presentations, simplified diagnostic criteria, and a literature review. Diagnostic Microbiology and Infectious Disease, 13, 521-525. doi:10.1016/0732-8893(90)90085-A
[7] Goldman, M., Chaudhary, U.B., Greist, A. and Fausel, C.A. (1998) Central nervous system infections due to Stomatococcusmucilaginosus in immunocompromised hosts. Clinical Infectious Diseases, 27, 1241-1246. doi:10.1086/515001
[8] Relrnan, D.A., Ruoff, K., Ferraro, M.J. (1987) Stomato- coccusmucilaginosusendocarditis in an intravenous drugabuser. Journal of Infectious Diseases, 155, 1080-1082. doi:10.1093/infdis/155.5.1080
[9] Coudron, P.E., Markowitz, S.M., Mohanty, L.B., Schatzki, P.F., Payne, J.M. (1987) Isolation of Stomatococcu-smucilaginosusfrom a drug user with endocarditis. Journal of Clinical Microbiology, 25, 1359-1363.
[10] Pinsky, R.L., Piscitelli, V. and Patterson, J.E. (1989) Endocarditis caused by relatively penicillin-resistant Stoma-tococcusmucilaginosus. Journal of Clinical Microbiology, 27, 215-221.
[11] Rubin, S.J., Lyons, R.W. and Murcia, A. J. (1978) Endocarditis associated with cardiac catheterization due to a gram-positive coccus designated Micrococcus mucila- ginosusincertaesedis. Journal of Clinical Microbiology, 7, 546-549.
[12] Schaad, U.B., Nelson, J.D., McCracken, G.H. Jr. (1981) Pharmacology and efficacy of vancomycin for staphylo-coccal infections in children. Rev Infect Dis., 3, S282- S288.
[13] Luer, M.S. and Hatton, J. (1993) Vancomycin administration into the cerebrospinal fluid: A review. Annals of Pharmacotherapy, 27, 912-921.
[14] Skogen, P.G., Kolmannskog, S. and Bergh, K. (2001) Bactericidal activity in cerebrospinal fluid by treating meningitis caused by Stomatococcusmucilaginosus with rifampicin, cefotaxime and vancomycin in a neutropenic child. Clinical Microbiology and Infection, 7, 39-42. doi:10.1046/j.1469-0691.2001.00182.x
[15] Von Eiff, C., Herman, M. and Peters, G. (1995) Antimicrobial susceptibilties of stomatococcus Mucilaginosa and of Micrococcus spp. Antimicrobial Agents and Chemotherapy, 39, 268-270.
[16] Kaiser, A.B. and McGee, Z.A. (1975) Aminoglycoside therapy of gram-negative bacillary meningitis. New Eng- land Journal of Medicine, 293, 1215-1220. doi:10.1056/NEJM197512112932401

  
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