[1]
|
Hart, D.A., et al. (2013) The knee as an integrated, inter-dependent organ system: Implications for injury risk, potential for effective repair, and possible impact on return to sport. British Journal of Sports Medicine, Review, Submitted.
|
[2]
|
Frank, C.B., et al. (2004) Regeneration and clinical issues in soft tissue reconstruction of the knee and shoulder. Annals of Biomedical Engineering, 32, 458-465. http://dx.doi.org/10.1023/B:ABME.0000017548.85451.b7
|
[3]
|
Loeser, R.F., Goldring, S.R., Scanzello, C.R. and Goldring, M.B. (2012) Osteoarthritis: A disease of the joint as an organ. Arthritis and Rheumatism, 64, 1697-1707. http://dx.doi.org/10.1002/art.34453
|
[4]
|
Hart, D.A., et al. (2002) Mechanobiology: Similarities and differences between in vivo and in vitro analysis at the functional and molecular levels. Recent Research Developments in Biophysics and Biochemistry, 2, 153-177.
|
[5]
|
Jadin, K.D., Wong, B.L., Bae, Kelvin, B.C., Williamson, A.K., Schumacher, B.L., Price, J.H. and Sah, R.L. (2005) Depth-varying density and organization of chondrocytes in immature and mature bovine articular cartilage assessed by 3D imaging and analysis. Journal of Histochemistry and Cytochemistry, 53, 1109-1119. http://dx.doi.org/10.1369/jhc.4A6511.2005
|
[6]
|
Jadin, K.D., Bae, W.C., Schumacher, B.L. and Sah, R.L. (2007) Three-dimensional (3-D) imaging of chondrocytes in articular cartilage: Growth-associated changes in cell organization. Biomaterials, 28, 230-239. http://dx.doi.org/10.1016/j.biomaterials.2006.08.053
|
[7]
|
Hellio Le Graverand, M-P., et al. (2001) The cells of the rabbit meniscus: Their arrangement, interrelationship, morphological variations and cytoarchitecture. Journal of Anatomy, 198, 525-535. http://dx.doi.org/10.1046/j.1469-7580.2000.19850525.x
|
[8]
|
Amiel, D., et al. (1995) Intrinsic properties of ACL and MCL cells and their responses to growth factors. Medical Science and Sports Exercise, 27, 844-851. http://dx.doi.org/10.1249/00005768-199506000-00008
|
[9]
|
Xie, J., Wang, C.L., Huang, D.-Y., Zhang, Y. Y., Xu, J. W., Kolesnikov, S.S., Paul Sung, K.L. and Zhao, H.C. (2013) TGF-beta1 induces the different expressions of lysyl oxidases and matrix metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after mechanical injury. Journal of Biomechanics, 46, 890-898. http://dx.doi.org/10.1016/j.jbiomech.2012.12.019
|
[10]
|
Thornton, G. and Hart, D.A. (2011) The interface of mechanical loading and biological variables as they pertain to the development of tendinosis. Journal of Muscu-loskeletal and Neuronal Interactions, 11, 94-105.
|
[11]
|
Natsu-ume, T., Majima, T., Reno, C., Shrive, N.G., Frank, C.B. and Hart, D.A. (2005) Evidence that menisci of the rabbit knee require mechanical loading to maintain homeostasis: Cyclic hydrostatic compression in vitro prevents derepression of catabolic genes. Journal of Orthopedic Science, 10, 396-405. http://dx.doi.org/10.1007/s00776-005-0912-x
|
[12]
|
Goulet, F., et al. (2011) Potential of tissue-engineered ligament substitutes for Ruptured ACL replacement. In: Regenerative Medicine and Tissue Engineering: From Cells to Organs, Book 2.
|
[13]
|
Lee, D.H., Sonn, C.H., Han, S.-B., Oh, Y., Lee, K.-M. and Lee, S.-H. (2012) Synovial fluid CD34 (-) CD44(+) CD90(+) mesenchymal stem cell levels are associated with the severity of primary knee osteoarthritis. Osteoarthritis and Cartilage, 20, 106-109. http://dx.doi.org/10.1016/j.joca.2011.11.010
|
[14]
|
Sekiya, I., Ojima, M., Suzuki, S., Yamaga, M., Horie, M., Koga, H., Tsuji, K., Miyaguchi, K., Ogishima, S., Tanaka, H. and Muneta, T. (2012) Human mesenchymal stem cells in synovial fluid increase in the knee with degenerated cartilage and osteoarthritis. Journal of Orthopedic Research, 30, 943-949. http://dx.doi.org/10.1002/jor.22029
|
[15]
|
Krawetz, R.J., Wu, Y.E., Martin, L., Rattner, J.B., Matyas, J.R. and Hart, D.A. (2012) Synovial fluid progenitors expressing CD90(+) from normal but not osteoarthritic joints undergo chondrogenic differentiation without micro-mass culture. PLoS One, 7, e43616. http://dx.doi.org/10.1371/journal.pone.0043616
|
[16]
|
Frank, C.B. (2004) Ligament structure, physiology and function. Journal of Musculoskeletal and Neuronal Interactions, 4, 199-201.
|
[17]
|
Thornton, G.M., Boorman, R.S., Shrive, N.G. and Frank, C.B. (2002) Medial collateral ligament autografts have increased creep response for at least two years and early immobilization makes this worse. Journal of Orthopedic Research, 20, 346-352. http://dx.doi.org/10.1016/S0736-0266(01)00100-0
|
[18]
|
Frank, C.B., Hart, D.A. and Shrive, N.G. (1999) Molecular biology and biomechanics of normal and healing ligaments—A review. Osteoarthritis and Cartilage, 7, 130-140. http://dx.doi.org/10.1053/joca.1998.0168
|
[19]
|
Achari, Y., Chin, J.W.S., Heard, B.J., Rattner, J.B., Shrive, N.G., Frank, C.B. and Hart, D.A. (2011) Molecular events surrounding collagen fibril assembly in the early healing rabbit medial collateral ligament-failure to recapitulate normal ligament development. Connective Tissue Research, 52, 301-312. http://dx.doi.org/10.3109/03008207.2010.524719
|
[20]
|
Khan, W.S. and Hardingham, T.E. (2012) Cartilage tissue engineering approaches applicable in orthopaedic surgery: The past, the present, and the future. Journal of Stem Cells, 7, 97-104.
|
[21]
|
Gomoll, A.H., Filardo, G., de Girolamo, L., Esprequeira-Mendes, J., Marcacci, M., Rodkey, W.G., Steadman, R.J., Zaffagnini, S. and Kon, E. (2012) Surgical treatment for early osteoarthritis. Part 1: Cartilage repair procedures. Knee Surgery, Sports Traumatology and Arthroscopy, 20, 450-466. http://dx.doi.org/10.1007/s00167-011-1780-x
|
[22]
|
Oldershaw, R.A. (2012) Cell sources for the regeneration of articular cartilage: The past, the horizon and the future. International Journal of Experimental Pathology, 93, 389-400.
|
[23]
|
Bentley, G., Bhamra, J.S., Gikas, P.D., Skinner, J.A., Carrington, R. and Briggs, T.W. (2013) Repair of osteochondral defects in joints-how to achieve success. Injury, 44, S3-S10. http://dx.doi.org/10.1016/S0020-1383(13)70003-2
|
[24]
|
Haddad, B., Pakravan, A.H., Konan, S., Adesida, A. and Khan, W. (2013) A systematic review of tissue engineered meniscus: Cell-based preclinical models. Current Stem Cell Research and Therapeutics, 8, 222-231. http://dx.doi.org/10.2174/1574888X11308030007
|
[25]
|
Trinh, T.Q., Harris, J.D., Siston, R.A. and Flanigan, D.C. (2013) Improved outcomes with combined autologous chondrocyte implantation and patellofemoral osteotomy versus isolated autologous chondrocyte implantation. Arthroscopy, 29, 566-574. http://dx.doi.org/10.1016/j.arthro.2012.10.008
|
[26]
|
Nakamura, N., et al. (2000) Decorin antisense gene therapy improves functional healing of early rabbit ligament scar with enhanced collagen fibrillogenesis in vivo. Journal of Orthopedic Research, 18, 517-523. http://dx.doi.org/10.1002/jor.1100180402
|
[27]
|
Nakamura, N., Hart, D.A., Frank, C.B., Marchuk, L.L., Shrive, N.G., Ota, N., Taira, K., Yoshikawa, H. and Kaneda, Y. (2001) Efficient transfer of intact oligonucleotides into the nucleus of ligament scar fibroblasts by HVJ-cationic liposomes is correlated with effective antisense gene inhibition. Journal of Biochemistry, 129, 755-759. http://dx.doi.org/10.1093/oxfordjournals.jbchem.a002916
|
[28]
|
Hart, D.A., et al. (2000) Complexity of determining cause and effect in vivo after antisense gene therapy. Clinical Orthopedics and Related Research, 379, S242-251. http://dx.doi.org/10.1097/00003086-200010001-00032
|
[29]
|
Hart, D.A., et al. (2000) Functional improvement in ligament scar tissue following anti-sense gene therapy: A model system for in vivo engineering of connective tissues. Gene Therapy and Molecular Biology, 4, 85-90.
|
[30]
|
Sanchez, M., et al. (2009) Platelet-rich therapies in the treatment of orthopaedic sport injuries. Sports Medicine, 39, 345-354.
|
[31]
|
Tschon, M., Fini, M., Giardino, R., Filardo, G., Dallari, D., Torricelli, P., Martini, L., Giavaresi, G., Kon, E., Maltarello, M.C., Nicolini, A. and Carpi, A. (2011) Lights and shadows concerning platelet products for musculo-skeletal regeneration. Frontiers of Bioscience (Elite Edition), 3, 96-107. http://dx.doi.org/10.2741/e224
|
[32]
|
Stanco, D., Vigano, M., Croiset, S.J. and De Girolamo, L. (2012) Applications and limits of platelet-rich plasma in sports related injuries. Journal of Biological Regulators and Homeostatic Agents, 26, 53S-61S.
|
[33]
|
Andia, I., Sánchez, M. and Maffulli, N. (2012) Joint pathology and platelet-rich plasma therapies. Expert Opinion on Biological Therapy, 12, 7-22. http://dx.doi.org/10.1517/14712598.2012.632765
|
[34]
|
Smyth, N.A., Murawski, C.D., Fortier, L.A., Cole, B.J. and Kennedy, J.G. (2013) Platelet-rich plasma in the pathologic processes of cartilage: A review of basic science evidence. Arthroscopy, 29, 1399-1409. http://dx.doi.org/10.1016/j.arthro.2013.03.004
|
[35]
|
Hildebrand, K.A., et al. (2002) Exogenous TGF-beta1 alone does not improve early rabbit MCL healing in vivo. Canadian Journal of Surgery, 45, 330-336.
|
[36]
|
Mammoto, T., Seerattan, R.A., Paulson, K.D., Leonard, C.A., Bray, R.C. and Salo, P.T. (2008) Nerve growth factor improves ligament healing. Journal of Orthopedic Research, 26, 957-964. http://dx.doi.org/10.1002/jor.20615
|
[37]
|
Ackermann, P., Salo, P. and Hart, D.A. (2009) Neuronal influences on tendon healing. Frontiers in Bioscience, 14, 5165-5187. http://dx.doi.org/10.2741/3593
|
[38]
|
Scharstuhl, A., et al. (2002) Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair. Journal of Immunology, 169, 507-514.
|
[39]
|
Alan, C., Kocoglu, H., Altintas, R., Alici, B. and Ersay, A.R. (2011) Protective effect of decorin on acute ischaemia-reperfusion injury in the rat kidney. Archives of Medical Science, 7, 211-216. http://dx.doi.org/10.5114/aoms.2011.22069
|
[40]
|
Kolb, M., Margetts, P.J., Galt, T., Sime, P.J., Xing, Z., Schmidt, M. and Gauldie, J. (2001) Transient trangene expression of decorin in the lung reduces the fibrotic response to bleomycin. American Journal of Respiratory and Critical Care Medicine, 163, 770-777. http://dx.doi.org/10.1164/ajrccm.163.3.2006084
|
[41]
|
Goyal, D., Keyhani, S., Lee, E.H. and Hui, J.H.P. (2013) Evidence-based status of microfracture technique: A systematic review of level I and II studies. Arthroscopy, 29, 1579-1588. http://dx.doi.org/10.1016/j.arthro.2013.05.027
|
[42]
|
Roelofs, A.J., Rocke, J.P.J. and De Bari, C. (2013) Cell-based approaches to joint surface repair: A research perspective. Osteoarthritis and Cartilage, 21, 892-900. http://dx.doi.org/10.1016/j.joca.2013.04.008
|
[43]
|
Gudas, R., Gudaite, A., Pocius, A., Gudiene, A., Cekanauskas, E., Monastyreckiene, E. and Basevicius, A. (2012) Ten-year follow-up of a prospective, randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint of athletes. American Journal of Sports Medicine, 40, 2499-2508. http://dx.doi.org/10.1177/0363546512458763
|
[44]
|
Gimble, J.M., E., Bunnell, B.A. and Guilak, F. (2012) Human adipose-derived cells: An update on the transition to clinical translation. Regenerative Medicine, 7, 225-235. http://dx.doi.org/10.2217/rme.11.119
|
[45]
|
Alegre-Aguaron, E., Desportes, P., García-álvarez, F., Castiella, T., Larrad, L. and Martínez-Lorenzo, M.J. (2012) Differences in surface marker expression and chondrogenic potential among various tissue-derived mesenchymal cells from elderly patients with osteoarthritis. Cells, Tissues and Organs, 196, 231-240.
|
[46]
|
Dhanasekaran, M., Indumathi, S., Kanmani, A., Poojitha, R., Revathy, K.M., Rajkumar, J.S. and Sudarsanam, D. (2012) Surface antigenic profiling of stem cells from human omentum fat in comparison with subcutaneous fat and bone marrow. Cytotechnology, 64, 497-509. http://dx.doi.org/10.1007/s10616-012-9427-4
|
[47]
|
Ando, W., Heard, B.J., Chung, M., Nakamura, N., Frank, C.B. and Hart, D.A. (2012) Ovine synovial membrane-derived mesenchymal progenitor cells retain the phenotype of the original tissue that was exposed to invivo inflammation: Evidence for a suppressed chondrogenic differentiation potential of the cells. Inflammation Research, 61, 599-608. http://dx.doi.org/10.1007/s00011-012-0450-x
|
[48]
|
Ando, W., et al. (2014) Clonal analysis of synovial fluid stem cells to characterize and identify stable MSC/MPC phenotypes in a porcine model: A cell source with enhanced commitment to the chondrogenic lineage. Cytotherapy, in press.
|
[49]
|
Manuelpillai, U., Moodley, Y., Borlongan, C.V. and Parolini, O. (2011) Amniotic membrane and amniotic cells: Potential therapeutic tools to combat tissue inflammation and fibrosis? Placenta, 32, S320-S325. http://dx.doi.org/10.1016/j.placenta.2011.04.010
|
[50]
|
Longo, U.G., Loppini, M., Berton, A., La Verde, L., Khan, W.S. and Denaro, V. (2012) Stem cells from umbilical cord and placenta for musculoskeletal tissue engineering. Current Stem Cell Research and Therapy, 7, 272-281. http://dx.doi.org/10.2174/157488812800793054
|
[51]
|
Bulman, S.E., Barron, V., Coleman, C.M. and Barry, F. (2013) Enhancing the mesenchymal stem cell therapeutic response: Cell localization and support for cartilage repair. Tissue Engineering (Part B) Reviews, 19, 58-68.
|
[52]
|
Izuta, Y., Ochi, M., Adachi, N., Deie, M., Yamasaki, T. and Shinomiya, R. (2005) Meniscal repair using bone marrow-derived mesenchymal stem cells: Experimental study using green fluorescent protein transgenic rats. Knee, 12, 217-223. http://dx.doi.org/10.1016/j.knee.2001.06.001
|
[53]
|
Heard, B.J., Fritzler, M.J., Wiley, J.P., McAllister, J., Martin, L., El-Gabalawy, H., Hart, D.A., Frank, C.B. and Krawetz, R. (2013) Intraarticular and systemic inflammatory profiles may identify patients with osteoarthritis. Journal of Rheumatology, 40, 1379-1387. http://dx.doi.org/10.3899/jrheum.121204
|
[54]
|
Harris, Q., Seto, J., O’Brien, K., Lee, P.S., Kondo, C., Heard, B.J., Hart, D.A. and Krawetz, R.J. (2013) Monocyte chemotactic protein-1 inhibits chondrogenesis of synovial mesenchymal progenitor cells: An in vitro study. Stem Cells, 31, 2253-2265. http://dx.doi.org/10.1002/stem.1477
|
[55]
|
Hart, D.A., Kydd, A.S., Frank, C.B. and Hildebrand, K.A. (2004) Tissue repair in Rheumatoid Arthritis: Challenges and opportunities in the face of a systemic inflammatory disease. Best Practices and Research in Clinical Rheumatology, 18, 187-202. http://dx.doi.org/10.1016/j.berh.2004.02.007
|
[56]
|
Abumaree, M., Al Jumah, M., Pace, R.A. and Kalionis, B. (2012) Immunosuppressive properties of mesenchymal stem cells. Stem Cell Reviews and Reports, 8, 375-392. http://dx.doi.org/10.1007/s12015-011-9312-0
|
[57]
|
Soleymaninejadian, E., Pramanik, K. and Samadian, E. (2012) Immunomodulatory properties of mesenchymal stem cells: Cytokines and factors. American Journal of Reproductive Immunology, 67, 1-8. http://dx.doi.org/10.1111/j.1600-0897.2011.01069.x
|
[58]
|
Koh, Y.G., Jo, S.B., Kwon, O.R., Suh, D.S., Lee, S.W., Park, S.H. and Choi, Y.J. (2013) Mesenchymal stem cell injections improve symptoms of knee osteoarthritis. Arthroscopy, 29, 748-755. http://dx.doi.org/10.1016/j.arthro.2012.11.017
|
[59]
|
Orozco, L., Munar, A., Soler, R., Alberca, M., Soler, F., Huguet, M., Sentís, J., Sánchez, A. and García-Sancho, J. (2013) Treatment of knee osteoarthritis with autologous mescenchymal stem cells: A pilot study. Transplantation, 95, 1535-1541. http://dx.doi.org/10.1097/TP.0b013e318291a2da
|
[60]
|
Hauser, R.A. and Orolfsky, A. (2013) Regenerative injection therapy with whole bone marrow aspirate for degenerative joint disease: A case series. Clinical and Medical Insights in Arthritis and Musculokeletal Disorders, 6, 65-72.
|
[61]
|
Goulet, F., Rancourt, D., Cloutier, R., Tremblay, P., Belzil, A.M., Lamontagne, J., Bouchard, M., Tremblay, J., Stevens, L.M., Labrosse, J., Langelier, E. and McKee, M.D. (2004) Torn ACL: A new bioengineered substitute brought from the laboratory to the knee joint. Applied Bionics and Biomechanics, 1, 115-121. http://dx.doi.org/10.1533/abib.2004.1.2.115
|
[62]
|
Frank, C.B. and Hart, D.A. (2004) Clinical application of tissue engineered tendon and ligament. In: Sandell, L. and Grodzinsky, A.J., Eds., Tissue Engineering in Musculo-skeletal Clinical Practice, AAOS, Rosemont, 2410256.
|
[63]
|
Hart, D.A., Shrive, N.G. and Goulet, F. (2005) Tissue engineering of ACL replacements. Sports Medicine and Arthroscopy Reviews, 13, 170-176. http://dx.doi.org/10.1097/01.jsa.0000173242.15191.70
|
[64]
|
Ando, W., Tateishi, K., Hart, D.A., Katakai, D., Tanaka, Y., Nakata, K., Hashimoto, J., Fujie, H., Shino, K., Yoshikawa, H. and Nakamura, N. (2007) Cartilage repair using an in vitro generated scaffold-free tissue-engineered construct derived from porcine synovial mesenchymal stem cells. Biomaterials, 28, 5462-5470. http://dx.doi.org/10.1016/j.biomaterials.2007.08.030
|
[65]
|
Ando, W., et al. (2012) Detection of abnormalities in the superficial zone of cartilage repaired using a tissue engineered construct derived from synovial stem cells. European Cells & Materials, 24, 292-307.
|
[66]
|
Matsusaki, M., Kadowaki, K., Tateishi, K., Higuchi, C., Ando, W., Hart, D.A., Tanaka, Y., Take, Y., Akashi, M., Yoshikawa, H. and Nakamura, N. (2009) Scaffold-free tissue-engineered construct-hydroxyapatite composites generated by an alternate soaking process: Potential for repair of bone defects. Tissue Engineering, Part A, 15, 55-63. http://dx.doi.org/10.1089/ten.tea.2007.0424
|
[67]
|
Moriguchi, Y., Tateishi, K., Ando, W., Shimomura, K., Yonetani, Y., Tanaka, Y., Kita, K., Hart, D.A., Gobbi, A., Shino, K., Yoshikawa, H. and Nakamura, N. (2013) Repair of meniscal lesions using a scaffold-free tissue-engineered construct derived from allogenic synovial MSCs in a miniature swine model. Biomaterials, 34, 2185-2193. http://dx.doi.org/10.1016/j.biomaterials.2012.11.039
|
[68]
|
Shimomura, K., Ando, W., Tateishi, K., Nansai, R., Fujie, H., Hart, D.A., Kohda, H., Kita, K., Kanamoto, T., Mae, T., Nakata, K., Shino, K., Yoshikawa, H. and Nakamura, N. (2010) The influence of skeletal maturity on allogenic synovial mesenchymal stem cell-based repair of cartilage in a large animal model. Biomaterials, 31, 8004-8011. http://dx.doi.org/10.1016/j.biomaterials.2010.07.017
|
[69]
|
Ando, W., Tateishi, K., Katakai, D., Hart, D.A., Higuchi, C., Nakata, K., Hashimoto, J., Fujie, H., Shino, K., Yoshikawa, H. and Nakamura, N. (2008) In vitro generation of a scaffold-free tissue-engineered construct (TEC) derived from human synovial mesenchymal stem cells: Biological and mechanical properties, and further chondrogenic potential. Tissue Engineering, Part A, 14, 2041-2049. http://dx.doi.org/10.1089/ten.tea.2008.0015
|