TITLE:
Treatment of Massive Low-Grade Chondrosarcoma of Nasal Septum with Helical Tomotherapy: A Case Report
AUTHORS:
Hamit Basaran, Timur Koca, Sibel Karaca, Ozlem Eser Kιlιnc, Fikriye Gul Karauc, Okan Özdemir, Ozan Kuduban, Arzu Tatar, Sare Şipal
KEYWORDS:
Chondrosarcoma, Image Guided, Intensity Modulated Radiation Therapy
JOURNAL NAME:
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology,
Vol.5 No.4,
November
7,
2016
ABSTRACT: Chondrosarcomas
are malignant bone tumors which develop as a cartilaginous differentiation of
primary mesenchymal cells and the second most frequently seen malignant tumor
of the bone after osteosarcoma. These malignancies are slowly growing
non-epithelial tumors with unknown etiology and most frequently seen during the
4 decades of life. They are frequently localized on pelvis, ribs and long
bones. Nasal septum CSs are very rarely seen malignancies. They originate from
septal mucosa or cartilage and it is difficult to make a diagnosis unless they
reach a certain size. A few cases of CSs with nasal septum have been reported
in the literature. In cases of CSs, surgery is the gold standard treatment
modality; however in surgically unresectable cases or close to margins,
radiotherapy plays a significant role in primary and adjuvant treatment. Based
on the position of the tumor in head and neck and extremely closeness of the
tumor to vital organs as optic nerve, chiasm and brain, image guided-intensity
modulated radiation therapy (IG-IMRT) becomes very effective and reliable
modalities and may be a favorable treatment alternative.