TITLE:
Determination of Triclocarban, Triclosan and Methyl-Triclosan in Environmental Water by Silicon Dioxide/Polystyrene Composite Microspheres Solid-Phase Extraction Combined with HPLC-ESI-MS
AUTHORS:
Yinan Wang, Pengfei Li, Yan Liu, Bing Chen, Jinyu Li, Xikui Wang
KEYWORDS:
Triclocarban; Triclosan; Solid-Phase Extraction; Silicon Dioxide/Polystyrene Composite Microspheres; HPLC-ESI-MS/MS
JOURNAL NAME:
Journal of Geoscience and Environment Protection,
Vol.1 No.2,
November
7,
2013
ABSTRACT: This paper developed a
sensitive and efficient analytical method for triclocarban (TCC), triclosan
(TCS) and Methyl-triclosan (MTCS) determination in environmental water, which
involves enrichment by using silicon dioxide/polystyrene composite microspheres
solid-phase extraction and detection with HPLC-ESI-MS. The influence of several operational
parameters, including the eluant and its volume, the flow rate and acidity of
water sample were investigated and optimized. Under the optimum conditions, the
limits of detection were 1.0 ng/L, 2.5 and 4.5 ng/L for TCC, TCS, and MTCS,
respectively. The linearity of the method was observed in the range of 5-2000 ng/L, with
correlation coefficients (r2) >.99. The spiked recoveries of TCC, TCS and MTCS in
water sampleswereachieved in the range
of 89.5% -96.8% with RSD below
5.7%. The proposed method has been successfully applied to analyze real water
samples and satisfactory results were achieved.