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has been cited by the following article:

• TITLE: Necrotizing Scleritis Associated with 5-Fluorouracil and Sub-Tenon’s Block in Patient with Previous Trabeculectomy: A Case Report

  AUTHORS: Tuan A. Tran, Jeremy O’Connor, Xavier Fagan, Tu Tran, Dan Nguyen

  KEYWORDS: Necrotizing Scleritis; 5-Fluorouracil; Sub-Tenon’s Block; Glaucoma

  JOURNAL NAME: Open Journal of Ophthalmology, Vol.3 No.3, August 7, 2013

  ABSTRACT: Necrotizing scleritis is the most severe form of scleritis with a significant threat to vision and globe integrity. It can be infectious, surgically induced necrotizing scleritis (SINS) or systemic autoimmune associated. We report a case of necrotizing scleritis associated with 5-fluorouracil (5-FU) at the site of sub tenon’s block in a patient with previous trabeculectomy. To our knowledge, this is the first reported case of necrotizing scleritis associated with 5-FU. This may implicate alternative approaches to local anaesthetic techniques when using adjunctive 5-FU.