Article citationsMore>>
E. Romano, M. Rossi, G. Ratzinger, M. A. de Cos, D. J. Chung, K. S. Panageas, J. D. Wolchok, A. N. Houghton, P. B. Chapman, G. Heller, J. Yuan and J. W. Young, “Peptide-Loaded Langerhans Cells, Despite Increased IL15 Secretion and T-Cell Activation in Vitro, Elicit Antitumor T-Cell Responses Comparable to Peptide-Loaded Monocyte-Derived Dendritic Cells in Vivo,” Clinical Cancer Research, Vol. 17, No. 7, 2011, pp. 1984-1997.
doi:10.1158/1078-0432.CCR-10-3421
has been cited by the following article:
-
TITLE:
Melanoma Immunotherapy: Overcoming Obstacles to Augment Anti-Tumor Immune Responses
AUTHORS:
Kristian M. Hargadon
KEYWORDS:
Melanoma; Tumor Immunotherapy; Dendritic Cell; Tumor Antigen; T Cell; Vaccine; Adoptive Transfer
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.3 No.2A,
June
20,
2013
ABSTRACT:
Melanoma is the most aggressive form
of skin cancer and accounts for the vast majority of skin cancer-related
deaths. Its ability to metastasize quickly, often before diagnosis, makes this
cancer difficult to treat with traditional therapies. The identification of
anti-melanoma immune responses in patients and the discovery of tumor antigens
targeted by these immune responses have paved the way for immunotherapy as a
novel approach to treating this cancer. In this review, the major
immunotherapies targeting these melanoma tumor antigens are discussed. The
advantages and limitations of peptide-, protein-, and gene-based vaccination
maneuvers and adoptive cell transfer therapies are emphasized. Recent insights
into melanoma immune evasion strategies are also highlighted, with particular
focus on how our increasing knowledge of tumor/immune cell interactions is
driving the development of novel immunotherapeutic strategies for the treatment
of melanoma.
Related Articles:
-
Casimir Komenan
-
Moawwad E. A. El-Mikkawy
-
Nowruz Delirezh, Seyed Mohammad Moazzeni, Fazel Shokri, Mohammad Ali Shokrgozar, Morteza Morteza Atri, Hamid Karbassian
-
Zheng Yuan
-
Yasue Takahashi, Kazunori Shimada, Katsuhiko Sumiyoshi, Takashi Kiyanagi, Makoto Hiki, Kosuke Fukao, Kuniaki Hirose, Rie Matsumori, Hiromichi Ohsaka, Atsumi Kume, Tetsuro Miyazaki, Hiroaki Miyajima, Isao Nagaoka, Hiroyuki Daida