H. Kanazawa, K. Yamamoto, Y. Y. Kashiwase, Y. Matsushima, N. Takai, A. Kikuchi, Y. Sakurai and T. Okano, “Analysis of peptides and proteins by temperature-res- ponsive chromatographic system using N-isopropylacry- laide polymer-modified columns,” J. Pharm. Biomed. Anal., Vol. 15, 1997, pp. 1545-1550.

has been cited by the following article:

• TITLE: Water—A Key Substance to Comprehension of Stimuli-Responsive Hydrated Reticular Systems

  AUTHORS: Miloslav Milichovsky

  KEYWORDS: Thermally Responsive Materials, Hydrogels, Hydration Forces, Volume Phase Transition

  JOURNAL NAME: Journal of Biomaterials and Nanobiotechnology, Vol.1 No.1, October 30, 2010

  ABSTRACT: Thermo-responsive hydrated macro-, micro- and submicro-reticular systems (TRHRS), particularly polymers forming hydrogels or similar networks, have attracted extensive interest because comprise biomaterials, smart or intelligent materials. Phase transition temperature (LCST or UCST, i.e. low or upper critical solution temperature, respectively) at about the TRHRS exhibiting a unique hydration-dehydration change is a typical characteristic. The characterization and division of the TRHRS are described followed by explanation of their behaviour. The presented original explanation is based on merely combination of basic thermodynamical state of individual useful macromolecule chains (long-chain or coil) with inter- and intra-mutual action of attractive and repulsive intramolecular hydration forces among them being strongly dependent upon temperature. Acquainted with this piece of knowledge, a theoretical concept of really biological systems movement, e.g. muscle tissues or artificial muscle etc., can be formulated.