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has been cited by the following article:

• TITLE: Descriptive and Analytical Study of Factors Associated with Mortality in Severe Malaria among Children in Dakar Emergency Departments from July to December 2022

  AUTHORS: Aliou Thiongane, Abou Ba, Fatou Ly, Aliou A. Ndongo, Djibril Boiro, Younoussa Kéita, Idrissa Basse, Babacar Niang, Indou Dême Ly, Yaye Joor Dieng, Djenaba Fafa Cissé, Ndiogou Seck, Lamine Thiam, Papa Moctar Faye, Amadou Lamine Fall, Assane Sylla, Ousmane Ndiaye

  KEYWORDS: Children, Malaria, Death, Factors

  JOURNAL NAME: Open Journal of Pediatrics, Vol.13 No.6, November 10, 2023

  ABSTRACT: Background: Malaria is the most widespread parasitic disease and remains a public health priority worldwide. The severe form is fatal if not treated early and appropriately. The aim was to carry out a descriptive and analytical study of the factors associated with mortality during severe malaria in children attending emergency departments in Dakar, Senegal. Methods: This is a prospective, observational and analytical study conducted over a 6-month period (July 1 to December 31, 2022), focusing on children hospitalized for severe malaria according to WHO severity criteria. Results: A total of 403 patients were hospitalized, including 78 cases of severe malaria (19.35%). Males predominated (60.26%) (sex ratio 1.51). The average age was 6.56 years [8 months - 14 years], with the [5 - 10 years] age group the most represented (40.26%). The average consultation time was 5.33 days (1 - 19 days). The main reasons for consultation were fever (70.51%), vomiting (24.35%) and convulsions (14.10%). Biological signs of severity were severe anemia (17.95%), renal failure (6.4%) and hypoglycemia (3.85%). Thrombocytopenia was noted in 52.56% of patients, including 32.05% of severe cases (sis in 61.41% of cases. Hyponatremia was noted in 39.74% of cases and hyperkalemia in 2 patients. Artesunate was the main drug used (93.59% of cases). Mortality was estimated at 1.5%. Factors leading to death were coma (P Conclusion: Malaria is still a public health problem, with a high mortality rate in emergency departments. Reducing this mortality rate requires effective management of the factors associated with death.