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has been cited by the following article:

• TITLE: Primary Left Atrial Intimal Sarcoma Disguised as Functional Mitral Stenosis: A Case Study

  AUTHORS: Zachary Visinoni, Frances Patmon, Rishi Menon

  KEYWORDS: Intimal Sarcoma, Cardiac Tumor, Mitral Stenosis, Atrial Mass

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.12 No.9, September 5, 2023

  ABSTRACT: A 66-year-old female with a 1-month history of increasing fatigue, dyspnea on exertion, and palpitations presented with clinical signs of heart failure. Chest computed tomography (CT) revealed a large, mobile left atrial (LA) mass attached to the mitral valve causing severe mitral stenosis and mitral regurgitation. The mass was surgically debulked and the mitral valve was replaced. Pathology revealed a poorly differentiated malignant spindle cell neoplasm with diffuse nuclear positivity of MDM2 and multifocal positivity of CDK4, consistent with intimal sarcoma. This case seeks to describe an uncommon presentation of a rare malignancy, and the surgical and medical management of the disease.