TITLE:
Primary Left Atrial Intimal Sarcoma Disguised as Functional Mitral Stenosis: A Case Study
AUTHORS:
Zachary Visinoni, Frances Patmon, Rishi Menon
KEYWORDS:
Intimal Sarcoma, Cardiac Tumor, Mitral Stenosis, Atrial Mass
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.12 No.9,
September
5,
2023
ABSTRACT: A 66-year-old female with a 1-month history of increasing fatigue, dyspnea on exertion, and palpitations presented with clinical signs of heart failure. Chest computed tomography (CT) revealed a large, mobile left atrial (LA) mass attached to the mitral valve causing severe mitral stenosis and mitral regurgitation. The mass was surgically debulked and the mitral valve was replaced. Pathology revealed a poorly differentiated malignant spindle cell neoplasm with diffuse nuclear positivity of MDM2 and multifocal positivity of CDK4, consistent with intimal sarcoma. This case seeks to describe an uncommon presentation of a rare malignancy, and the surgical and medical management of the disease.