TITLE:
Transforming Molecules into Medicines: Role of CDMOS in Phase-Appropriate Technology Transfers in Advancing Pharmaceutical Innovation
AUTHORS:
Kishore Kumar Hotha
KEYWORDS:
Technology Transfer, CDMO, Innovation, Preclinical, GMP, Phase Appropriate Method Development, Phase-1, Commercial, Manufacturing, Continuous Improvement, Lifecycle Management
JOURNAL NAME:
Advances in Chemical Engineering and Science,
Vol.13 No.3,
June
15,
2023
ABSTRACT: CDMOs are emerging as critical
drivers of innovation within the pharmaceutical and biotech industries. As the
pharmaceutical industry continues to evolve, we can expect to see CDMOs play an
increasingly important role in drug development and manufacturing. Many
companies within these sectors are now leveraging the expertise of CDMOs
through technology transfers to foster innovation and enhance the development
of new drug products. In the extensive field of drug development, technology
transfer plays a crucial role at multiple stages, ranging from preclinical
phases to commercialization. By working closely with drug developers, CDMOs can
ensure that technologies are transferred seamlessly between phases of drug
development, allowing for a more efficient and
cost-effective development process. CDMOs also
bring a wealth of experience in various areas of drug development, including
process development, analytical testing, quality control, and manufacturing.
This expertise, combined with a focus on innovation, can help drug developers
to overcome technical challenges and optimize their drug development programs.
CDMOs can provide drug developers with various manufacturing capabilities, from
small-scale clinical trials to large-scale commercial production. This
flexibility allows drug developers to focus on their core competencies while
relying on CDMOs to provide the necessary infrastructure and support for drug
manufacturing. The critical role of
CDMOs in advancing pharmaceutical innovation in phase-appropriate technology transfer where there will be a lot of
effort and patience with strong technical expertise is required. This article
explores the various types of Technology transfer from preclinical to
commercial stages and successful strategies to foster innovation.