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has been cited by the following article:

• TITLE: Persistent Pseudomonas Infection Mastoiditis—Local Antibiotic Treatment Is Superior than Systemic

  AUTHORS: Siti Aisyah Mohamed, Roslim-Siti Norain, Shahrul Hitam, Asma Binti Abdullah

  KEYWORDS: Antibiotic, Cholesteatoma, Drug-Resistant, Mastoidectomy, Mastoiditis

  JOURNAL NAME: International Journal of Otolaryngology and Head & Neck Surgery, Vol.12 No.3, May 15, 2023

  ABSTRACT: Mastoiditis is a common complication of acute otitis media. It is common in younger age compared to adulthood. Mastoiditis occurs when an otitis media infection spread directly to involve the bone of mastoid air cell causing osteitis. Cholesteatoma can contribute to the development of mastoiditis. This typically leads to breakdown of some of the fine bony trabeculae of mastoid cells producing a coalescent mastoiditis with an emphyema in mastoid antrum. Cholesteatoma can contribute to the development of mastoiditis. The common treatment for mastoiditis is intravenous antibiotic. Our cases show that local antibiotic treatment is superior compared to systemic antibiotic in treating multi-drug resistant chronic. Pseudomonas mastoiditis compared to intravenous antibiotic. However, if it presents together with cholesteatoma the main treatment is still early mastoidectomy.