Felippe Gonçalves-de-Albuquerque, C., Ribeiro Silva, A., Ignácio da Silva, C., Caire Castro-Faria-Neto, H. and Burth, P. (2017) Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy. Molecules, 22, Article No. 578.
https://doi.org/10.3390/molecules22040578

has been cited by the following article:

• TITLE: The Continuous Relative Deficiency of Intracellular Potassium Is a Core Mechanism for the Occurrence and Metastasis of Tumor Cancer Cells

  AUTHORS: Jiapei Dai

  KEYWORDS: Potassium Ions, Relative Deficiency of Potassium Ions, Na +, K + -ATPase, Tumor Cancer Cells, Metastasis of Cancer Cells

  JOURNAL NAME: Natural Science, Vol.14 No.11, November 10, 2022

  ABSTRACT: The core mechanism for occurrence of tumor cancer cells is related to the continuous relative deficiency of potassium ions in the cells of organs and tissues, which results in embryonic like proliferation and differentiation in the affected cells. The purpose of the metastasis of cancer cells is to obtain and utilize the potassium resources in other organs in body. However, if the overall potassium storage in body is obviously insufficient, the metastatic cancer cells still fail to achieve the purpose of obtaining enough potassium and turn into normal cells, further proliferation and differentiation of cancer cells will continue, and finally will lead to functional decline in the organs and tissues affected or death. Therefore, the key means to prevent and treat tumors and cancers is to ensure the normal and balanced potassium ions in cells in various organs and tissues, so as to avoid the formation of tumors and cancer cells caused by obvious deficiency of potassium ions.