TITLE:
Advanced Endoscopic Palliation of Unresectable Periampullary Carcinoma: A Systematic Review
AUTHORS:
Shailesh Simkhada, Shravana Aryal, Albert D. Osei, Ashik Pokharel, Rami Matar, Michael Maitar
KEYWORDS:
Periampullary Malignancies, Endoscopic Ultrasound, Celiac Plexus Neurolysis, ERCP, EUS-BD, EUS-GE
JOURNAL NAME:
Open Journal of Gastroenterology,
Vol.12 No.10,
September
26,
2022
ABSTRACT: Background and Aims: Periampullary malignancies often present at an advanced unresectable stage requiring palliation of symptoms for the better quality of life. Though they require multispecialty support; role of endoscopic interventions in palliation is paramount because of the advancement in technology and increase experience of Gastroenterologist. Methods: We did extensive review of articles regarding endoscopic advances in the management of Unresectable Periampullary Malignancies. Several systematic reviews, Meta analysis, and Randomized controlled trials published over the last 2 decades were thoroughly searched on PUBMED and GOOGLE SCHOLAR. Results: Advanced Endoscopic procedures have been emerging as a superior modality than conventional measures because of minimal invasiveness and greater clinical and technical success. Conclusion: Periampullary malignancies often present at an advanced unresectable stage requiring palliation of symptoms for the better quality of life. Several endoscopic interventions have already been established as the standard of care in palliation of symptoms of unresectable periampullary malignancies, we can say with confidence that with growing advances in EUS, advancement in technologies and increasing experiences, the role of gastroenterologist will be pivotal in these groups of patients.