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Pereira de Souza Neto, E., Grousson, S., Duflo, F., Ducreux, C., Joly, H., Convert, J.,, et al. (2011) Predicting Fluid Responsiveness in Mechanically Ventilated Children under General Anaesthesia Using Dynamic Parameters and Transthoracic Echocardiography. British Journal of Anaesthesia, 106, 856-864.
https://doi.org/10.1093/bja/aer090
has been cited by the following article:
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TITLE:
Neuroblastoma in Children: Intraoperative Goal Directed Therapy, Intraoperative and Postoperative Outcomes
AUTHORS:
Claudine Kumba
KEYWORDS:
Neuroblastoma, Children, Intraoperative Goal Directed Therapies, Postoperative Outcomes
JOURNAL NAME:
Open Journal of Internal Medicine,
Vol.11 No.4,
December
3,
2021
ABSTRACT: Background: Neuroblastoma is the most common tumor in children. Anesthetic management can be challenging due to the localization and catecholamine-secreting characteristics of the tumor. We undertook a secondary analysis in a previous study to describe patients who underwent neuroblastoma resection. Objective: To describe intraoperative and postoperative outcomes in patients who underwent neuroblastoma resection and to propose optimal intraoperative management for postoperative outcome improvement. Methods: This was a secondary analysis of children who underwent neuroblastoma resection in the initial retrospective study. Results: There were 16 patients with a mean age of 39.3 ± 22.1 months. Seven (43.8%) patients presented with intraoperative or postoperative complications. One (6.3%) patient had intraoperative broncho-laryngospasm and difficult intubation. Two (12.5%) patients had intraoperative hemorrhagic shock. One patient (6.3%) had postoperative renal failure. Two patients (12.5%) had postoperative respiratory failure, and 3 (18.8%) patients had postoperative cardiocirculatory failure. One (6.3%) had postoperative pulmonary sepsis and septicemia. Thirteen (81.3%) patients were intraoperatively transfused. There was no in-hospital mortality. Conclusion: In this cohort, 43.8% of the patients had intraoperative and or postoperative complications in terms of organ dysfunction or sepsis. 81.3% of the patients received intraoperative transfusion. Neuroblastoma surgery can be a challenging situation where cardiovascular instability, high blood loss and transfusion requirements can be encountered. Consequently, preoperative preparation and optimal intraoperative management with validated tools in children could be necessary for a better postoperative outcome in this surgical setting.
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