TITLE:
Trends and Disparities in Breast Cancer Incidence-Mortality Rates of Black-White Women in the U.S.: 2000-2016
AUTHORS:
Ishrat Binte Aftab, Akash Ahmed, Sinthia Kabir Mumu, Tonima Fairooz Mouly, Drishti Sharad Commar
KEYWORDS:
Black, White, Non-Hispanic White, Cancer, Breast, SEER, Incidence, Mortal-ity, Race/Ethnicity, United States
JOURNAL NAME:
Advances in Breast Cancer Research,
Vol.10 No.4,
October
11,
2021
ABSTRACT: Introduction: Female Breast cancer is the second leading cause of cancer-related deaths in the U.S.
While the incidence rate is lower in Hispanic-Black, the mortality rate is higher compared to Non-Hispanic
White. This study investigates the trends of incidence and mortality rate of
breast cancer in the U.S.: 2000-2016. It further explores the racial disparities between these two
races. Method: Data for four age groups (15 - 39 yrs, 40 - 64 yrs, 65 - 74 yrs, 75+ yrs) of Hispanic-Black and
Non-Hispanic White women for breast cancer were extracted from SEER; age-adjusted rate (U.S. 2000
standard population). Primary trend analysis
was done with PyCharm 2020.3.3. (line charts) and regression models to
check any significant increase or decrease over the years were done with JoinPoint
4.8.0.1 (APC, 95% CI, significant p-value: Result: Incidence rate is higher in Non-Hispanic White women, whereas
mortality rate is higher in Hispanic Black. The 40 - 64 yrs age groups showed an increase in incidence rate
for Hispanic Black women, whereas an decrease for White women. The least vulnerable
group, 15 - 39 yrs age showed an increase in
incidence rate in Non-Hispanic White women. The mortality rate was declining overall for both races. Conclusion: Disparities in oncologic healthcare, insurance system and
socio-economic factors are possibly responsible for the higher
mortality in Black American women. Improvements in these factors may
reduce racial differences.