TITLE:
Role of Oral Misoprostol in First Trimester Abortion: A Prospective Study at CMH, Dhaka, Bangladesh
AUTHORS:
S. K. Chowdhury, M. Z. Hussain
KEYWORDS:
Role of Oral Misoprostol, First Trimester Abortion
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.10 No.1,
January
13,
2020
ABSTRACT: Background: Misoprostol has been
used for medical abortion. We conducted this prospective study to see the
efficacy of oral misoprostol in our tertiary Hospital. Objective: Objective of this study was to assess the
efficiency, safety and compliance of
misoprostol in first trimester abortion. Materials
and Methods: This prospective study was undertaken in obstetrics and gynecology dept of CMH Dhaka, Bangladesh from July 2014 up to Dec 2014. A total 50
patients of incomplete abortion (54%), missed abortion (30%), anembryonic
pregnancy (14%) and inevitable abortion (2%) of s of
gestation were the targeted population. Study population was diagnosed from history, physical examination and ultrasonogram had
received 600 microgram misoprostol orally. If the pregnancy was not completely
evacuated at this time another dose of misoprostol was given.
All women returned for follow-up care 7 days later. If the pregnancy was not
completely evacuated at this time, women underwent immediate surgical
evacuation. Efficacy was defined as the percent of women discharged from the
study without need for surgical intervention. Results: 30 patients had complete evacuation after 1st dose, 12 cases needed 2nd dose
and only 2 cases needed 3rd dose. Remaining 6 cases needed
surgical evacuation. Efficacy was satisfactory (85%) and analysis revealed
statistically significant (p 0.05). Conclusion: Management of first trimester abortion with oral misoprostol is highly
effective and highly acceptable.