TITLE:
Sero-Prevalence of HBV, HCV and HEV among the Egyptian Pregnant Females
AUTHORS:
Suzan Samir Elsharkawy, Wael Samir Elgazayerli
KEYWORDS:
Viral Hepatitis, Hepatitis B Virus, Hepatitis C Virus, Hepatitis E Virus, Pregnant Women
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.9 No.10,
October
25,
2019
ABSTRACT: Background: Viral hepatitis in pregnant women can be caused by multiple types of
hepatitis viruses and can cause a wide range of symptoms and complications,
ranging from asymptomatic infection to maternal and fetal deaths. Objective: The aim of this study was to evaluate the sero-prevalence and the associated factors of viral hepatitis B (HBV), viral hepatitis C (HCV)
and viral hepatitis E (HEV) among the Egyptian pregnant females. Methods: This cross-sectional study was conducted in the period from January to July 2017 in two selected antenatal
clinics; El-shat by
maternity university hospital at Alexandria city and El-Behera health insurance
antenatal clinic at Damanhur city on 261 apparently healthy gravid women.
Eligible women were evaluated by a questionnaire about socio-demographic data and viral
serological tests were done at El-shat by maternity University Hospital Laboratory. Results: The overall HBs-Ag sero-prevalence in the pregnant women included in this study was 7
cases (2.7%) and HCV-RNA PCR was 4 cases (1.5%). Of the total study
participants, none of them (0%) were anti-HEV IgM positive and 48 cases (18.4%)
were anti-HEV IgG positive. According
to our results, neither
age of the woman, place of residence, past family
history of hepatitis virus infection nor having a pet animal had any strong
association to be considered as an associated factor for acquiring HEV infection. Conclusion: Although it seems that there are many improvements in the prevalence of
different hepatitis viruses in the country, hepatitis viral infections are
still high enough to continue their preventive programs and health education,
to protect the mothers and their fetuses from the hazardous effects of these
serious infections.