TITLE:
One-month immunotherapy trial in treatment-failed TB patients
AUTHORS:
Olga V. Arjanova, Dmitry A. Butov, Natalia D. Prihoda, Svetlana I. Zaitzeva, Larisa V. Yurchenko, Nina I. Sokolenko, Anna L. Stepanenko, Tatyana S. Butova, Elena A. Grinishina, Olga A. Maksimenko, Vichai Jirathitikal, Aldar S. Bourinbaiar, Valery M. Frolov, Galyna A. Kutsyna
KEYWORDS:
Biomarker; HIV; Inflammation; MDR-TB; Mycobacterium; Survival; Treatment Failure; Vaccine
JOURNAL NAME:
Open Journal of Immunology,
Vol.1 No.2,
September
30,
2011
ABSTRACT: reatment failed TB patients have very limited chances of survival. Open label trial of daily oral pill of V-5 Immunitor (V5) was conducted in 48 treatment-failed TB patients on palliative support consisting of isoniazid (H) and rifampicin (R). The subjects had the following forms of TB; cavitary: disseminated: MDR-TB: DR-TB: TB/HIV at 35:13:7:4:1 ratio. After 1 month 62.5% of V5-treated patients experienced negative sputum smear conversion (P 2 respectively (P