TITLE:
Solvent- and Catalyst-Free Microwave-Assisted Decarboxylation of Malonic Acid Derivatives
AUTHORS:
Fanny Araceli Cabrera-Rivera, Luis Gabriel Hernández-Vázquez, Patricia Flores-Sánchez, Maria Durán-Galván, Jaime Escalante
KEYWORDS:
Microwave, Decarboxylation, Malonic Acid Derivatives, Solvent-Free, Catalyst-Free, Green Chemistry
JOURNAL NAME:
Green and Sustainable Chemistry,
Vol.7 No.4,
November
15,
2017
ABSTRACT: It has been found that microwave assisted decarboxylation of malonic acid derivatives can be achieved under solvent-free and catalyst free conditions. This new method produces the corresponding carboxylic acid in a pure manner and with a high yield in a very short reaction time: 3 - 10 min. In general terms, the condition under which this reaction is carried out accelerates the decarboxylation significantly of a series of disubstituted malonic acid derivatives, and makes this new process efficient, easy and environmentally friendly.