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has been cited by the following article:

• TITLE: Point-of-Care Testing Using Three Dimensional Optical Biosensor Based on Microfluidic Technology

  AUTHORS: Chunxiu Liu, Haoyuan Cai, Jian Jia, Tianyang Cao, Tong Li, Tianjun Ma, Chang Liu

  KEYWORDS: Point-of-Care Testing (POCT), Three Dimensional Optical Chip, hs-CRP

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.4 No.12, December 1, 2016

  ABSTRACT: We have presented a three dimensional optical protein chip that fulfills the demanding for point-of-care diagnostics in terms of ease-of-use (one step assay), miniaturization (5 μl). The artful combination of magnetic nanoparticles on chip and total internal reflection imaging (TIRI) technology permits the sensitive and rapid detection of hs-CRP (high-sensitivity C-reactive protein). The whole test was complete within 10 min using “all in one step” assay with a limit of detection of 0.1 ng/mL hs-CRP. The measuring range for hs-CRP could be extended to 10 ng/mL. The chip can also be used to detect more parameters in blood samples.