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http://dx.doi.org/10.1002/humu.20961

has been cited by the following article:

• TITLE: Computational Molecular Analysis of the Sequences of BMP15 Gene of Ruminants and Non-Ruminants

  AUTHORS: Bwaseh S. Bibinu, Abdulmojeed Yakubu, Steven B. Ugbo, Ndu I. Dim

  KEYWORDS: BMP15, Sequences, SNPs, Phylogeny, Ruminants, Non-Ruminants

  JOURNAL NAME: Open Journal of Genetics, Vol.6 No.2, June 6, 2016

  ABSTRACT: Bone morphogenetic protein 15 (BMP15) is a member of the transforming growth factor β (TGFβ) super family that is expressed by oocytes and plays key roles in granulosa cell development and fertility in animal. This study investigated the molecular genetic variation of BMP15 gene of some selected mammalian species with a view to providing relevant genetic information for breeding and selection programmes in the studied species using computational methods. A total of thirty seven (37) BMP15 nucleotide sequences comprising goats (18), sheep (6), cattle (6), swine (4) and chicken (3) were retrieved from the GenBank. Sequence alignment, translation and comparison of the BMP15 gene of the various species were done with ClustalW. High degree of polymorphism of BMP15 gene was observed among the studied species. The significant value (P bovidae family (goat, sheep and cattle). The present information could guide future efforts involving selection of markers of fecundity to improve genetically livestock species in Nigeria.