TITLE:
Pro-Oxidant Antioxidant Balance in Inflammatory Bowel Disease
AUTHORS:
Abbas Esmaelzadeh, Hassan Vosooghinia, Mohammad Reza Sheikhian, Hadi Bagheri Hosseini, Daryoush Hamidi Alamdari, Fatemeh Ahmadi, Maryam Emadzadeh, Seyed Mahdi Pakdaman Shahri
KEYWORDS:
Inflammatory Bowel Disease, Pro-Oxidant Antioxidant Balance, Oxidative Stress, Ulcerative Colitis, Crohn’s Disease
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.7 No.5,
May
27,
2016
ABSTRACT: Background: Inflammatory bowel disease (IBD) is associated with increased morbidity and incident of colon cancer; however its etiology is still unclear. Currently, one of the most probable pathogenesis patterns is increased permeability of bowel membrane and it seems that oxidative stress plays an important role in this pathway. This study was done to assess the pro-oxidant antioxidant balance (PAB) in these patients. Materials: This was a cross sectional study of 2 groups including 50 patients with diagnosed IBD and 50 healthy controls. Patients were selected purposively from those referring to adult gastroenterology clinic in 2013. SPSS (ver11.5) has been. A P value