Article citationsMore>>
Perez-Areales, F.J., Di Pietro, O., Espargaro, A., Vallverdu-Queralt, A., Galdeano, C., Ragusa, I.M., Viayna, E., Guillou, C., Clos, M.V., Perez, B., Sabate, R., Lamuela-Raventos, R.M., Luque, F.J. and Munoz-Torrero, D. (2014) Shogaol-Huprine Hybrids: Dual Antioxidant and Anticholinesterase Agents with β-Amyloid and Tau Anti-Aggregating Properties. Bioorganic & Medicinal Chemistry, 22, 5298-5307.
http://dx.doi.org/10.1016/j.bmc.2014.07.053
has been cited by the following article:
-
TITLE:
Synthesis and Bioactivity of Natural Occurring Petasin-Like Derivatives as Antitumor Agents
AUTHORS:
Xiaolong Shi, Saiyang Zhang, Jianghao Wang, Tingyu Li, Junju Liu, Yi Hou, Lei Liu, Dongjun Fu, Haiwei Xu, Hongmin Hongmin, Yanbing Zhang
KEYWORDS:
Petasin, SK-N-SH, Mechanism, Derivative, Antiproliferative Activity
JOURNAL NAME:
Open Journal of Medicinal Chemistry,
Vol.5 No.2,
June
8,
2015
ABSTRACT: Petasin is a potential antitumor against human neuroblastoma cell SK-N-SH by inhibiting the ERK1/2 phosphorylation. In view of its great activity and new antiproliferative mechanisms, a series of petasin derivatives were designed and synthesized, which showed great antiproliferative activity. Among them compounds 1h and 1f were more effective against SK-N-SH cells than petasin with the IC50 values of 0.87 and 2.63 μM, respectively.
Related Articles:
-
Fossou Jean-Luc Hervé Kouadio, Mamadou Sangare, N’Guessan Nestor Houssou, Marc Ephrem Allialy, Sagbrou Chérubin Djro
-
Jai Dev Chandel, Nand Lal Singh
-
Stanislas T. Kouame, Mathias G. Tahi, Aïdara Sekou, Christian Cilas, Selastique D. Akaffou
-
György Steinbrecher, Alberto Sonnino, Giorgio Sonnino
-
Adam Berłowski, Katarzyna Zawada, Iwona Wawer, Katarzyna Paradowska