Syrtsova, L.A., Sanina, N.A., Lyssenko, K.A., Kabachkov, E.N., Psikha, B.L., Shkondina, N.I., Pokidova, O.V., Kotelnikov, A.I. and Aldoshin, S.M. (2014) Reversible Dissociation and Ligand-Glutathione Exchange Reaction in Binuclear Cationic Tetranitrosyl Iron Complex with Penicillamine. Bioinorganic Chemistry and Applications, 2014, Article ID: 641407.
http://dx.doi.org/10.1155/2014/641407

has been cited by the following article:

• TITLE: Interaction of Hemoglobin with Binuclearcationic Tetranitrosyl Iron Complex with Penicillamine. Cations Binding Sites

  AUTHORS: Lidia Syrtsova, Natalia Sanina, Boris Psikha, Ildar Tukhvatullin, Natal’ja Shkondina, Olesia Pokidova, Alexander Kotelnikov

  KEYWORDS: Biomedicine, Iron-Sulfur Cluster, Ligand Binding, Heme, Nitric Oxide

  JOURNAL NAME: Advances in Biological Chemistry, Vol.5 No.3, April 28, 2015

  ABSTRACT: In this paper, the kinetics of the interaction of the nitrosyl iron complex with the ligands penicillamine [Fe2(SC5H11NО2)2(NO)4]SO4·5H2O (I) with deoxyhemoglobin (Hb) was studied. The kinetic modeling method defined the number of binding (I) molecules and equilibrium constant of the coupling reaction of (Biomedicine, Iron-Sulfur Cluster, Ligand Binding, Heme, Nitric Oxide ) with Hb (Ks). At equimolar concentrations of (I) and Hb (2 × 10−5 M), the Hb molecule binds only one (I) with Ks equal to 4.3 × 107 M−1. When increasing the (Biomedicine, Iron-Sulfur Cluster, Ligand Binding, Heme, Nitric Oxide ) concentration, the number of binding sites of Hb increases and Ks decreases. These results are analyzed in accordance with the data on the existence of cations binding sites in Hb.