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http://dx.doi.org/10.1021/jo015730j

has been cited by the following article:

• TITLE: Simple Reduction of Hydantoins with Sodium Borohydride

  AUTHORS: Jun-Ichi Yamaguchi, Emiko Shibuta, Yoshie Oishi

  KEYWORDS: Hydantoin, Reduction, Imidazolidinone

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.4 No.5, December 26, 2014

  ABSTRACT: The reduction of various hydantoins with sodium borohydride gave the corresponding 4-hydroxy- 2-imidazolidinones in high yields. In contrast, reduction employing a boron trifluoride etherate-sodium borohydride system generated 2-imidazolidinones. In both reductions, the reactivity of the hydantoin was dependent on its substituents. The Lewis acid-promoted reactions of a 4-hydroxy-2-imidazolidinone with nucleophiles were also investigated.