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has been cited by the following article:

• TITLE: Hyperthyroidism Due to Papillary Thyroid Carcinoma Associated with Ductal Breast Carcinoma

  AUTHORS: Maria de Fátima Borges, Ilka Mara Borges Botelho Modolo, Rodrigo Gimenez Pissutti Modolo, Lilian Carla Silva, Luciene Mayumi Sato, Rogério Costa Tiveron, Delcio Scandiuzzi, Marcus Aurelho Lima

  KEYWORDS: Papillary Carcinoma, Hyperthyroidism, Breast Carcinoma, Thyroid, Metastasis

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.3 No.8, August 14, 2014

  ABSTRACT: Thyroid tumors are usually associated with euthyroidism, and hyper functioning tumors are rare. There are few reports of carcinomas associated with hyperthyroidism. The aim of this study is to describe a case of hyper functioning papillary carcinoma associated with breast carcinoma. We present a 46-year-old woman that was referred for investigation of thyroid and breast nodules detected by routine ultrasound. She presented with hyperthyroidism and enlarged left thyroid lobe with fibroelastic consistency. Investigation demonstrated papillary carcinoma with follicular hyperactivity and invasive ductal carcinoma of the breast. The patient developed metastases 6 months later and died. This study demonstrates that hot thyroid nodules may harbor malignant tumors and should be punctured. The association with breast adenocarcinoma and the unfavorable outcome suggest higher aggressiveness of this tumor in the presence of hyperthyroidism.