TITLE:
Cyclic Bis(3'-5')diadenylic Acid (c-di-AMP) Analogs Promote the Activities of Photosynthesis and Respiration of Chlamydomonas reinhardtii
AUTHORS:
Takafumi Tezuka, Hiroshi Shirouzu, Keigo Ishida, Noritaka Suzuki, Takuya Matsuo, Kin-ichi Oyama, Setsuyuki Aoki, Masaki Tsukamoto
KEYWORDS:
c-di-AMP; O2 Evolution (Photosynthesis); O2 Uptake (Respiration); Chlamydomonas reinhardtii
JOURNAL NAME:
American Journal of Plant Sciences,
Vol.5 No.1,
January
7,
2014
ABSTRACT:
Physiological changes in the photosynthesis,
respiration and cell division of Chlamydomonas
reinhardtii, a freshwater green alga, in response to adenine nucleotides
were investigated. In advance of this investigation, two adenine nucleotides, di(2'-O-methyl)-cyclic
bis(3'-5')diadenylic acid (1) and its N-benzoyl-protected analog 2 were synthesized from the commercially
available adenosine phosphoramidite. The respective analogs significantly
promoted the cell division (cell number) of C.
reinhardtii strains 137c mt+ and BR mt+. Moreover,
they significantly enhanced the O2 evolution (photosynthesis) and O2 uptake (respiration) of both strains. c-di-AMP analogs seem to play an
effective role as a physiological activator in planta.