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Weatherley, B.D., Cotter, G., Dittrich, H.C., DeLucca, P., Mansoor, G.A., Bloomfield, D.M., et al. (2010) Design and rationale of the PROTECT study: A placebo-controlled randomized study of the selective A1 adenosine receptor antagonist rolofylline for patients hospitalized with acute decompensated heart failure and volume overload to assess treatment effect on congestion and renal function. Journal of Cardiac Failure, 16, 25-35. doi:10.1016/j.cardfail.2009.10.025

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