Scientific Research An Academic Publisher
OPEN ACCESS
Add your e-mail address to receive free newsletters from SCIRP.
Select Journal AA AAD AAR AASoci AAST ABB ABC ABCR ACES ACS ACT AD ADR AE AER AHS AID AiM AIT AJAC AJC AJCC AJCM AJIBM AJMB AJOR AJPS ALAMT ALC ALS AM AMI AMPC ANP APD APE APM ARS ARSci AS ASM BLR CC CE CellBio ChnStd CM CMB CN CRCM CS CSTA CUS CWEEE Detection EMAE ENG EPE ETSN FMAR FNS GEP GIS GM Graphene GSC Health IB ICA IIM IJAA IJAMSC IJCCE IJCM IJCNS IJG IJIDS IJIS IJMNTA IJMPCERO IJNM IJOC IJOHNS InfraMatics JACEN JAMP JASMI JBBS JBCPR JBiSE JBM JBNB JBPC JCC JCDSA JCPT JCT JDAIP JDM JEAS JECTC JEMAA JEP JFCMV JFRM JGIS JHEPGC JHRSS JIBTVA JILSA JIS JMF JMGBND JMMCE JMP JPEE JQIS JSBS JSEA JSEMAT JSIP JSS JSSM JST JTR JTST JTTs JWARP LCE MC ME MI MME MNSMS MPS MR MRC MRI MSA MSCE NJGC NM NR NS OALib OALibJ ODEM OJA OJAB OJAcct OJAnes OJAP OJApo OJAppS OJAPr OJAS OJBD OJBIPHY OJBM OJC OJCB OJCD OJCE OJCM OJD OJDer OJDM OJE OJEE OJEM OJEMD OJEpi OJER OJF OJFD OJG OJGas OJGen OJI OJIC OJIM OJINM OJL OJM OJMC OJMetal OJMH OJMI OJMIP OJML OJMM OJMN OJMP OJMS OJMSi OJN OJNeph OJO OJOG OJOGas OJOp OJOph OJOPM OJOTS OJPathology OJPC OJPChem OJPed OJPM OJPP OJPS OJPsych OJRA OJRad OJRD OJRM OJS OJSS OJSST OJST OJSTA OJTR OJTS OJU OJVM OPJ POS PP PST PSYCH SAR SCD SGRE SM SN SNL Soft SS TEL TI UOAJ VP WET WJA WJCD WJCMP WJCS WJET WJM WJNS WJNSE WJNST WJV WSN YM
More>>
(2007) Alzheimer’s disease facts and figures. Alzheimer’s Association. http://www.alz.org/national/documents/report_2007factsandfigures.pdf
has been cited by the following article:
TITLE: The tomography dementia rating scale (TDR)—The rating scale of Alzheimer’s disease stages
AUTHORS: Ivan V. Maksimovich
KEYWORDS: Alzheimer's Disease; AD Stage; TDR; CDR; Dementia; Hippocampus; Atrophy of the Temporal Lobes of the Brain
JOURNAL NAME: Health, Vol.4 No.9A, September 28, 2012
ABSTRACT: The purpose of this research is to develop a morphologically determined scale—the Tomography Dementia Rating scale (TDR) to diagnose AD stages, based on the measurement of the severity of voluminal atrophic changes of the temporal lobes of the brain detected among patients during CT and MRI at various stages of the disease. The research included 140 patients aged 28 - 79. Test Group comprised 81 patients aged 34 - 79 suffering from various AD stages. Control Group consisted of 59 patients aged 28 - 78 who had various types of brain lesions with manifestations of dementia and cognitive impairment but who did not suffer from AD. CT and MRI data obtained has made it possible to create a scale that allows determining the severity of atrophic changes in the temporal lobes at each stage of AD development: 1) Pre-clinical AD stage—TDR-0: temporal lobes atrophy with a 4% - 8% decrease in tissue mass (corresponds to 26 - 28 MMSE points); 2) Early AD Stage—mild dementia—TDR-1: temporal lobes atrophy with a 9% - 18% decrease in tissue mass (corresponds to CDR-1 and to 20 - 25 MMSE points); 3) Middle AD stage—moderate dementia—TDR-2: temporal lobes atrophy with a 19% - 32% decrease in tissue mass (corresponds to CDR-2 and to 12 - 19 MMSE points); 4) Late AD stage—heavy dementia—TDR-3: temporal lobes atrophy with a 33% - 62% decrease in tissue mass (corresponds to CDR-3 and to 7 - 11 MMSE points). Thereby, the developed Tomography Dementia Rating scale (TDR) complements the Clinical Dementia Rating scale (CDR) and allows a correct and objective determination of AD stages as well as an easy differentiation of existing lesions with neurodegenerative changes characteristic for other diseases accompanied by dementia and cognitive impairment.
Related Articles:
Vascular factors in Alzheimer’s disease
Ivan V. Maksimovich
DOI: 10.4236/health.2012.429114 4,597 Downloads 7,567 Views Citations
Pub. Date: September 28, 2012
Mitochondrial Dysfunction and Alzheimer’s Disease
Fatimah M. Albrekkan, Marie Kelly-Worden
DOI: 10.4236/ojemd.2013.32A003 4,594 Downloads 8,503 Views Citations
Pub. Date: May 20, 2013
The role of APP in Alzheimer’s disease
Leland Pung, Xingjun Wang, Min Li, Lei Xue
DOI: 10.4236/aad.2013.22008 2,970 Downloads 6,603 Views Citations
Pub. Date: June 17, 2013
Cognitive assessment in Alzheimer’s disease
Mario A. Parra
DOI: 10.4236/aad.2013.24016 5,812 Downloads 10,772 Views Citations
Pub. Date: December 3, 2013
Association between Caregiver Quality of Life and the Care Provided to Persons with Alzheimer’s Disease: Systematic Review
Afeez Abiola Hazzan, Harry Shannon, Jenny Ploeg, Parminder Raina, Mark Oremus
DOI: 10.4236/aad.2014.31006 4,497 Downloads 7,809 Views Citations
Pub. Date: March 24, 2014