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M. Kulldorff, R. Heffernan, J. Hartman, R. M. Assun??o and F. Mostashari, “A Space-Time Permutation SCAN Statistic for the Early Detection of Disease Outbreaks,” PLoS Medicine, Vol. 2, No. 3, 2005, pp. 216-224. doi:10.1371/journal.pmed.0020059

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