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has been cited by the following article:

• TITLE: Efficacy and Tolerance Study of an Oligopeptide with Potential Anti-Aging Activity

  AUTHORS: Athanasia Varvaresou, Spyridon Papageorgiou, Evangelia Protopapa, Alexandra Katsarou

  KEYWORDS: Oligopeptide-20, Anti-Aging Cosmetics, Efficacy and Tolerance, Profilometry, Self-Evaluation, TEWL and Skin Barrier

  JOURNAL NAME: Journal of Cosmetics, Dermatological Sciences and Applications, Vol.1 No.4, December 28, 2011

  ABSTRACT: Background Oligopeptide-20 acts as positive regulator of cell proliferation and increases collagen and hyaluronic acid levels in keratinocyte and fibroblast cultures. Methods After randomization half the face of twenty volunteers was treated twice daily for two months with the oligopeptide-20 cream (0.003% w/w, 300 ppm) and the other half with the vehicle. Skin bioengineering was used to estimate the effects on human skin. Results The average number and width of wrinkles (Sew, 11.7%, p